Results 101 to 110 of about 2,415,477 (301)
Expanded access to secondary schooling in Sub-Saharan Africa: key planning and finance issues [PDF]
, 2007 This paper makes the case for managed expansion of secondary schooling in Sub-Saharan Africa. The great majority of secondary age African children remain excluded from access to good quality secondary schooling.
Lewin, Keith M
core
, 2019 The World Health Organization's Expanded Programme on Immunization (WHO-EPI) was developed to ensure that all children have access to common childhood vaccinations.
G Şahin +5 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Have Differences in Credit Access Diminished in an Era of Financial Market Deregulation? [PDF]
Over the past few decades, financial markets have become increasingly deregulated and household debt has expanded, sometimes rapidly. It is possible that greater deregulation led to improved credit access--measured by loan denials, discouraged ...
Christian E. Weller
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Creating a Pathway to a Better Financial Future: Developing State Strategies for Asset Development and Wealth Creation for People with Disabilities [PDF]
, 2011 Dedicated economic advancement strategies - such as savings and building assts, homeownership, and entrepreneurship -- are increasingly viewed as an important part of public policy efforts to give people with disabilities expanded access to the labor ...
Candace Baldwin, Megan O'Neill
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
FDICIA's emergency liquidity provisions [PDF]
An exploration of the change in standards for Federal Reserve discount window access by nonbanks encompassed in the Federal Deposit Insurance Corporation Improvement Act of 1991 (FDICIA), concluding that although it retrenched the federal financial ...
Walker F. Todd
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source