It Is a Good Time to Expand Your Circle! [PDF]
The recently passed health care reform law, the Patient Protection and Affordable Care Act includes a mandate for the Centers for Medicare and Medicaid Services (CMS) to test innovative payment models to reduce program expenditures while preserving or enhancing quality(1).
Stephan R, Thilen, Bobbie Jean, Sweitzer
openaire +2 more sources
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Social and emotional learning for the greater good: Expanding the circle of human concern
The central argument of this article is that educators can empower young people to address global challenges by actively helping them to expand their circle of concern beyond themselves and their social circles.
Aakash A. Chowkase
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The EFL Methodology Course in Chile: SLTE in the Expanding Circle
With the growth of EFL instruction worldwide, there has been increasing interest in how English teachers are prepared, yet little research has addressed these programs in foreign contexts.
Annjeanette Martin
doaj +1 more source
MOVE STRUCTURES AND THEIR RHETORICAL VERBS OF RESEARCH ARTICLE ABSTRACTS ACROSS ENGLISHES
Genre-based studies on moves structure of research article (RA) abstracts have established variations across cultures. However, previous studies included at most two countries for comparisons of abstracts written by native against non-native speakers ...
Abdul Wahid Ibrahim Tocalo
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
INTEGRATION AND NETWORKING MECHANISMS OF PROMOTING SCIENTIFIC AND INNOVATION ACTIVITY IN THE HIGHER EDUCATION SYSTEM OF KAZAKHSTAN [PDF]
The article considers the theoretical and practical issues of development networking integration forms of the universities in the innovation sphere on modern stage.
А. Taubayev
doaj +1 more source
On the Fixed Circle Problem on Metric Spaces and Related Results
The fixed-circle issue is a geometric technique that is connected to the study of geometric characteristics of certain points, and that are fixed by the self-mapping of either the metric space or of the generalized space.
Nabil Mlaiki +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

