Results 61 to 70 of about 46,064 (302)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

English as a lingua franca in Southeast Asia's Expanding Circle

open access: yes
The distinction Kachru made between countries of the Outer and Expanding Circles was that Outer Circle countries had been colonies of English-speaking empires where English played institutional roles and where local varieties of English had developed. In
Kirkpatrick, A
core   +1 more source

Optimal linear response for expanding circle maps

open access: yes, 2023
We consider the problem of optimal linear response for deterministic expanding maps of the circle. To each infinitesimal perturbation $\dot{T}$ of a circle map $T$ we consider (i) the response of the expectation of an observation function and (ii) the ...
Froyland, Gary, Galatolo, Stefano
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

State of the Field: Human Sociality and our Expanding Circle

open access: yes, 2021
The first part of this essay provides a brief summary of this journal’s first editorial, which examined eight needed developments and eight critical contexts for global inquiry.
McCool, Matthew
core  

Proceedings from the Third International Post-Tuberculosis Symposium: expanding the circle

open access: yesIJTLD Open
SUMMARY: In light of the recent growth in interest and knowledge of post-TB sequelae, there were high levels of engagement during the 3rd International Post-Tuberculosis Symposium held in Stellenbosch, South Africa.
B.W. Allwood   +35 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

English as a Lingua Franca: A New Variety in the New Expanding Circle?

open access: yesNJES: Nordic Journal of English studies, 2006
The traditional tripartite model of English world-wide has so far ignored one of the most important functions of English today, namely that of a lingua franca between non-native speakers.
Sandra Mollin
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Evaluation in Australasia: An Overview of Recent Developments

open access: yesJournal of MultiDisciplinary Evaluation, 2007
Evaluation activities continue to develop throughout Australasia as evidenced by the Australasia Evaluation Society (AES) expanding its circle of influence and reaching out to its neighbors in Vietnam and China.
Wes Martz
doaj   +1 more source

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