Results 141 to 150 of about 3,162,794 (289)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Tratamiento prefermentativo flash expansion en uvas Merlot y Ribier y su efecto sobre la calidad del vino [PDF]

, 2001
Resumen (Spanish, English)51 p.Se desarrolló un estudio destinado a evaluar el efecto producido por el tratamiento prefermentativo de uvas "flash expansión", sobre la calidad del vino.
Fuentes Ramirez, Julio Alejandro, Laurie Gleisner, Víctor Felipe (Prof. Guía), Moreno Simunovic, Yerko (Prof. Informante)   +2 more
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Un sastre a la medida: breves comentarios para el desarrollo de proyectos built-to-suit

Derecho & Sociedad, 2020
En este artículo se plantea una primera aproximación a los proyectos built to suit (BTS) desde un punto de vista económico y legal, tanto para facilitar a los operadores jurídicos su entendimiento como para dar sentido y pautas claras respecto de su ...
Vega Mere, Yuri, Muñoz Sivana, Anthony
doaj  

¿Canarios en la mina? La prensa y los riesgos de ‘burbuja inmobiliaria’ en España [PDF]

, 2012
Análisis de la cobertura de la burbuja inmobiliaria en la prensa de referencia española: El País, El Mundo, ABC, Expansión y Cinco Días (2003 ...
Arrese, Á. (Ángel), Vara-Miguel, A. (Alfonso)   +1 more
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium.

Gastroenterology, 2011
Toshiro Sato, D. Stange, M. Ferrante, R. Vries, J. van Es, Stieneke van den Brink, W. V. van Houdt, A. Pronk, J. V. van Gorp, P. Siersema, H. Clevers   +10 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Mandatory audit firm rotation in Spain: a policy that was never applied [PDF]

In recent international debates on auditing regulation, Spain has assumed a real prominence as a claimed practical example of where a policy of mandatory audit firm rotation did not work and was duly abolished.
NIEVES CARRERA
core  

Impacto de las adiciones para concreto en la reducción de la permeabilidad al ion cloruro vs la relación agua cemento [PDF]

, 2015
Trabajo de InvestigaciónLos elementos en la construcción, fabricados en concreto reforzado y que se encuentran expuestos al ataque de los cloruros tienen un periodo corto de servicio.
Carmona-Herrera, Rodrigo Alonso, Montaña-Muñoz, Cristhian Camilo   +1 more
core