Results 111 to 120 of about 491,048 (337)

An analytical approach to obtain exact solutions of some space-time conformable fractional differential equations

Advances in Differential Equations, 2019
In this paper, the sine-Gordon expansion method is used to obtain analytical solutions of the conformable space-time generalized reaction Duffing model and conformable space-time Eckhaus equation with the aid of symbolic computation.
N. Kadkhoda, H. Jafari
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Adaptive quadrature by expansion for layer potential evaluation in two dimensions

, 2018
When solving partial differential equations using boundary integral equation methods, accurate evaluation of singular and nearly singular integrals in layer potentials is crucial.
Klinteberg, Ludvig af, Tornberg, Anna-Karin   +1 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Piecewise Analytical Approximation Methods for Initial-Value Problems of Nonlinear Ordinary Differential Equations

Mathematics
Piecewise analytical solutions to scalar, nonlinear, first-order, ordinary differential equations based on the second-order Taylor series expansion of their right-hand sides that result in Riccati’s equations are presented.
Juan I. Ramos
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Frequency Response Analysis of Buck-Boost Inverter

Mìkrosistemi, Elektronìka ta Akustika, 2019
The paper deals with processes analysis in inverter circuits. These processes are described by differential equations with periodical coefficients. Since control signals and voltages operating in an inverter circuit are independent theirs frequencies are
Igor Yevheniiovych Korotyeyev
doaj   +1 more source

Some expansion formulas for a class of singular partial differential equations [PDF]

Proceedings of the American Mathematical Society, 1982
We obtain a generalization of the Almansi’s expansion and the Lord Kelvin principle for solutions of a class of iterated elliptic or ultrahyperbolic equations. We also obtain some homogeneous function expansions for solutions of the same equations.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Steady-State Analysis of Inverter Working with Varied Load

Mìkrosistemi, Elektronìka ta Akustika, 2019
The paper deals with an analysis of steady-state behaviours in inverter circuits. Transient and steady-state processes in inverter circuits are described by differential equations with periodical coefficients.
Igor Yevheniiovych Korotyeyev
doaj   +1 more source