Results 71 to 80 of about 1,216,327 (284)

Reinforcement Learning for Efficient Power Systems Planning: A Review of Operational and Expansion Strategies

open access: yesEnergies
The efficient planning of electric power systems is essential to meet both the current and future energy demands. In this context, reinforcement learning (RL) has emerged as a promising tool for control problems modeled as Markov decision processes (MDPs)
Gabriel Pesántez   +4 more
doaj   +1 more source

Long term planning for EFA and the MDGs: modes and mechanisms [PDF]

open access: yes, 2007
This discussion paper provides an overview and analytic guide to long term planning of education systems in the context of Education for All and the Millennium Development Goals.
Lewin, Keith M
core  

Energy planning for metropolitan context: potential and perspectives of sustainable energy action plans (seaps) of three italian big cities [PDF]

open access: yes, 2016
Energy retrofitting of existing building stock and new expansion of urban settlements entail a new relationship between consumption and production sites.
Berghi, Saverio
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Proactive transmission expansion planning with storage considerations

open access: yesEnergy Strategy Reviews, 2019
Under the current European market environment, transmission companies have to decide network expansion by maximizing social welfare. However, generation companies (GENCOs) decide their capacity expansion with the aim of maximizing their own profit.
Isaac-Camilo Gonzalez-Romero   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Transmission and Generation Expansion Planning Considering Virtual Power Lines/Plants, Distributed Energy Injection and Demand Response Flexibility from TSO-DSO Interface

open access: yesEnergies
This article presents a computational model for transmission and generation expansion planning considering the impact of virtual power lines, which consists of the investment in energy storage in the transmission system as well as being able to determine
Flávio Arthur Leal Ferreira   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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