Results 91 to 100 of about 8,179,783 (370)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Coupled Effect of Expansion Ratio and Blade Loading on the Aerodynamics of a High-Pressure Gas Turbine

open access: yes, 2017
The need of a continuous improvement in gas turbine efficiency for propulsion and power generation, as well as the more demanding operating conditions and power control required to these machines, still ask for great efforts in the design and analysis of
P. Gaetani, G. Persico, A. Spinelli
semanticscholar   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Effect of Cowpea Lignocellulosic Fibers as a Low‐Value Reinforcing Filler on the Properties of Poly(butylene succinate‐co‐adipate) Bio‐Composite Foams

open access: yesMacromolecular Materials and Engineering
Herein, fully bio‐based and biodegradable bio‐composite foams are produced from poly(butylene succinate‐co‐adipate) (PBSA), reinforced with low‐value cowpea lignocellulosic fibers, and azodicarbonamide as a chemical blowing agent.
Mondli A. Masanabo   +3 more
doaj   +1 more source

Parametric analysis of diffuser requirements for high expansion ratio space engine [PDF]

open access: yes
A supersonic diffuser ejector design computer program was developed. Using empirically modified one dimensional flow methods the diffuser ejector geometry is specified by the code.
Anderson, P. G., Wojciechowski, C. J.
core   +1 more source

Specific heat amplitude ratios for anisotropic Lifshitz critical behaviors

open access: yes, 2003
We determine the specific heat amplitude ratio near a $m$-axial Lifshitz point and show its universal character. Using a recent renormalization group picture along with new field-theoretical $\epsilon_{L}$-expansion techniques, we established this ...
C. C. Becerra   +25 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Clearing vs. Leakage: Does Note monopoly Increase Money and Credit Cycles? [PDF]

open access: yes
The effects of note monopolisation on the amplitude of money and credit cycles are studied. Swedish bank data for 1871–1915 reveal that money cycles became smaller, but credit cycles larger, after the Bank of Sweden gained a note monopoly in 1904. At the
Hortlund, Per
core   +3 more sources

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