Results 11 to 20 of about 11,040 (207)

A Bioconjugate Vaccine Against Extra-Intestinal Pathogenic Escherichia coli (ExPEC)

Vaccines
Background: Extra-intestinal pathogenic Escherichia coli (ExPEC) represents a major global public health challenge due to its ability to cause diverse clinical infections, including urinary tract infections, bacteremia, neonatal meningitis, and sepsis ...
Linhui Hao, Wenhua Huang, Yan Guo, Xiankai Liu, Jun Wu, Li Zhu, Chao Pan, Hengliang Wang   +7 more
doaj   +4 more sources

Urinary tract infections attributed to diverse ExPEC strains in food animals: evidence and data gaps [PDF]

Frontiers in Microbiology, 2015
Between 70 and 95% of urinary tract infections (UTI) are caused by strains of Escherichia coli. These strains, often termed Extraintestinal Pathogenic E.
Randall S Singer, Randall S Singer
doaj   +4 more sources

LY294002 and LiCl Mitigate Neonatal ExPEC Meningitis Through Akt/GSK3β Signaling Modulation. [PDF]

Mediators Inflamm
Background Neonatal purulent meningitis (NPM) is a life‐threatening condition associated with high mortality rates and a substantial risk of severe long‐term neurological sequelae among survivors. Extraintestinal pathogenic Escherichia coli (ExPEC) is the predominant causative agent of NPM and exhibits multidrug resistance.
Zou P, Xiao R, Sheng S, Zhang P, Huang P, Du Y, Chen Y, Wang Y.   +7 more
europepmc   +3 more sources

Multidrug-Resistant Strain ExPEC Isolat Asal Puyuh (Coturnix coturnix japonica)

Jurnal Sain Veteriner, 2023
AbstractExtraintestinal Escherichia coli (ExPEC) causes colibacillosis in poultry, including quail. ExPEC is a pathogenic E. coli that causes colibacillosis outside the gastrointestinal tract of poultry, in the form of peritonitis, pericarditis, salpingitis, synovitis, osteomyelitis, septicemia, pneumonitis, nephritis, pleurisy, proventriculitis and ...
Prihtiyantoro, Wahyu, Purnomo, Agus, ., Sudarisman, ., Khusnan   +3 more
openaire   +5 more sources

Spondylodiscitis in a healthy 12-year-old girl with Extraintestinal pathogenic Escherichia coli (ExPEC) bacteraemia [PDF]

BMC Infectious Diseases, 2017
Escherichia coli (E. coli) is rarely implicated in bone or joint infections in children.We discuss the case of a healthy 12-year-old girl with an E. coli bacteraemia and a T11-T12 spondylodiscitis revealed by magnetic resonance imaging. The strain harboured serogroup O1:K1 and virulence factors common to highly virulent extra intestinal pathogenic E ...
J. Gaschignard, G. Geslain, C. Mallet, M. Lorrot, N. Blot, M. Alison, S. Bonacorsi   +6 more
openaire   +4 more sources

Vaccines against extraintestinal pathogenic Escherichia coli (ExPEC): progress and challenges

Gut Microbes
The emergence of antimicrobial resistance (AMR) is a principal global health crisis projected to cause 10 million deaths annually worldwide by 2050. While the Gram-negative bacteria Escherichia coli is commonly found as a commensal microbe in the human gut, some strains are dangerously pathogenic, contributing to the highest AMR-associated mortality ...
Ling Qiu, Dylan Chirman, Justin R. Clark, Yikun Xing, Haroldo Hernandez Santos, Ellen E. Vaughan, Anthony W. Maresso   +6 more
openaire   +6 more sources

Genetic Characterization of ExPEC-Like Virulence Plasmids among a Subset of NMEC

PLOS ONE, 2016
Neonatal Meningitis Escherichia coli (NMEC) is one of the most common causes of neonatal bacterial meningitis in the US and elsewhere resulting in mortality or neurologic deficits in survivors. Large plasmids have been shown experimentally to increase the virulence of NMEC in the rat model of neonatal meningitis.
Nicholson, Bryon A., West, Aaron C., Mangiamele, Paul, Barbieri, Nicolle, Wannemuehler, Yvonne, Nolan, Lisa, Logue, Catherine M., Li, Ganwu   +7 more
openaire   +7 more sources

Novel Pathways Revealed in Bursa of Fabricius Transcriptome in Response to Extraintestinal Pathogenic Escherichia coli (ExPEC) Infection

PLOS ONE, 2015
Extraintestinal pathogenic Escherichia coli (ExPEC) has major negative impacts on human and animal health. Recent research suggests food-borne links between human and animal ExPEC diseases with particular concern for poultry contaminated with avian pathogenic E. coli (APEC), the avian ExPEC.
Sun, Hongyan, Liu, Peng, Nolan, Lisa, Lamont, Susan   +3 more
openaire   +7 more sources

Identification of Risk Factors for Invasive Extraintestinal Pathogenic Escherichia coli (ExPEC) Disease [PDF]

Antimicrobial Stewardship & Healthcare Epidemiology, 2021
Background: A pathogenic group of invasive extraintestinal pathogenic (ExPEC) Escherichia coli possess the ability to infect normally sterile body sites and cause severe invasive ExPEC disease (IED). ExPEC is a leading cause of bacteremia and sepsis worldwide and is associated with older age and multidrug-resistant infections.
Clarke, Erik, Geurtsen, Jeroen, Spiessens, Bart, Chehoud, Christel   +3 more
openaire   +1 more source

Trends in ExPEC serogroups in the UK and their significance [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2016
Extra-intestinal pathogenic Escherichia coli are a significant cause of urinary tract infection and bacteraemia within the UK. We sought to identify the serogroups of 658 E. coli isolates collected in the UK between January 2011 and March 2012, to better understand the ExPEC population and understand the relevance of serogroups in this pathotype ...
H. Ciesielczuk, C. Jenkins, M. Chattaway, M. Doumith, R. Hope, N. Woodford, D. W. Wareham   +6 more
openaire   +3 more sources