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Antimicrobial resistance and vaccines in Enterobacteriaceae including extraintestinal pathogenic Escherichia coli and Klebsiella pneumoniae [PDF]

npj Antimicrobials and Resistance
Antimicrobial-resistant Enterobacteriaceae are increasingly a clinical challenge. In particular, extraintestinal pathogenic Escherichia coli and Klebsiella pneumoniae threaten public health.
Adriana Cabrera, Emily Mason, Liam P. Mullins, Manish Sadarangani   +3 more
doaj   +2 more sources

Global survey of extraintestinal pathogenic Escherichia coli identifies stable serogroup-virulence-resistance linkages [PDF]

Genome Medicine
Background Extraintestinal pathogenic Escherichia coli (ExPEC) is a leading cause of urinary tract infections, sepsis, and neonatal meningitis globally.
Mengjie Li, Xiao Liu, Ruiting Lan, Yanwen Xiong, Yanqing Che, Yixin Mao, Hongzhou Li, Guodong Yan, He Gao, Xuemei Bai, Zhiwen Sun, Xiaoning Liu, Duochun Wang   +12 more
doaj   +2 more sources

CRISPR-Cas9-mediated IncF plasmid curing in extraintestinal pathogenic Escherichia coli [PDF]

Microbiology Spectrum
IncF plasmids are commonly found in extra-intestinal pathogenic Escherichia coli (ExPEC) strains, serving as reservoirs for antimicrobial resistance (AMR) genes and virulence factors, persistently coexisting with ExPEC lineages. Multidrug-resistant (MDR)
Liang Chen, Gisele Peirano, Kelly Yen, Bingjie Wang, Austin Terlecky, Rebekah DeVinney, Barry N. Kreiswirth, Johann D. D. Pitout   +7 more
doaj   +2 more sources

Outer membrane protein A (OmpA) of extraintestinal pathogenic Escherichia coli [PDF]

BMC Research Notes, 2020
Objective Extraintestinal Pathogenic E. coli (ExPEC), are responsible for host diseases such as Neonatal Meningitis Escherichia coli (NMEC), the second-leading cause of neonatal bacterial meningitis, Avian Pathogenic E.
Daniel W. Nielsen, Nicole Ricker, Nicolle L. Barbieri, Heather K. Allen, Lisa K. Nolan, Catherine M. Logue   +5 more
doaj   +2 more sources

Diagnosis of extraintestinal pathogenic Escherichia coli pathogenesis in urinary tract infection [PDF]

Current Research in Microbial Sciences
Extra-intestinal pathogenic Escherichia coli (ExPEC) is a virulent pathogen found in humans that causes the majority of urinary tract infections, and other infections such as meningitis and sepsis.
Deenadayalan Karaiyagowder Govindarajan, Biniam Moges Eskeziyaw, Kumaravel Kandaswamy, Degisew Yinur Mengistu   +3 more
doaj   +2 more sources

Vaccines against extraintestinal pathogenic Escherichia coli (ExPEC): progress and challenges [PDF]

Gut Microbes
The emergence of antimicrobial resistance (AMR) is a principal global health crisis projected to cause 10 million deaths annually worldwide by 2050. While the Gram-negative bacteria Escherichia coli is commonly found as a commensal microbe in the human ...
Ling Qiu, Dylan Chirman, Justin R. Clark, Yikun Xing, Haroldo Hernandez Santos, Ellen E. Vaughan, Anthony W. Maresso   +6 more
doaj   +2 more sources

O-specific polysaccharide confers lysozyme resistance to extraintestinal pathogenic Escherichia coli

Virulence, 2018
Extraintestinal pathogenic Escherichia coli (ExPEC) is the leading cause of bloodstream and other extraintestinal infections in human and animals. The greatest challenge encountered by ExPEC during an infection is posed by the host defense mechanisms ...
Yinli Bao, Haobo Zhang, Xinxin Huang, Jiale Ma, Catherine M. Logue, Lisa K. Nolan, Ganwu Li   +6 more
doaj   +2 more sources

Occurrence, antimicrobial resistance, and potential zoonosis risk of avian pathogenic Escherichia coli in Indonesia: A review [PDF]

International Journal of One Health, 2022
Avian pathogenic Escherichia coli (APEC) causes avian colibacillosis or colibacillosis and is a major endemic disease of poultry worldwide, including in Indonesia.
Freshinta Jellia Wibisono, Mustofa Helmi Effendi, Freshindy Marissa Wibisono   +2 more
doaj   +1 more source

Antiviral Resistance and Phage Counter Adaptation to Antibiotic-Resistant Extraintestinal Pathogenic Escherichia coli

mBio, 2021
Extraintestinal pathogenic Escherichia ...
Keiko C. Salazar, Li Ma, Sabrina I. Green, Jacob J. Zulk, Barbara W. Trautner, Robert F. Ramig, Justin R. Clark, Austen L. Terwilliger, Anthony W. Maresso   +8 more
doaj   +1 more source

Characteristics, pathogenic mechanism, zoonotic potential, drug resistance, and prevention of avian pathogenic Escherichia coli (APEC)

Frontiers in Microbiology, 2022
Although most Escherichia coli (E. coli) strains are commensal and abundant, certain pathogenic strains cause severe diseases from gastroenteritis to extraintestinal infections. Extraintestinal pathogenic E.
Jiangang Hu, Dossêh Jean Apôtre Afayibo, Beibei Zhang, Hong Zhu, Lan Yao, Weiqi Guo, Xinyu Wang, Zhiyang Wang, Di Wang, Haoheng Peng, Mingxing Tian, Jingjing Qi, Shaohui Wang   +12 more
doaj   +1 more source