Results 141 to 150 of about 533,786 (316)

O DESEMPENHO DAS UNIVERSIDADES PÚBLICAS PORTUGUESAS SEGUNDO SEUS ALUNOS: ANÁLISE DE EFICIÊNCIA POR MEIO DO DATA ENVELOPMENT ANALYSIS

open access: yesRevista Gestão Universitária na América Latina, 2012
The objective of this investigation was to evaluate the performance of Portuguese Public Universities, based on the expectations and satisfaction of their students and using the DEA method (Data Envelopment Analysis).
Emerson Wagner Mainardes   +2 more
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Signaling Effects of Foreign Exchange Interventions and Expectation Heterogeneity among Traders [PDF]

open access: yes
This paper explores whether official intervention signaling effects on short-run exchange rate movements depend on market conditions. We find evidence that announced interventions significantly affect the level and reduce the volatility of the yen/dollar
Iwatsubo, Kentaro, Shimizu, Junko
core  

Expectation Violations, Expectation Change, and Expectation Persistence: The Scientific Landscape as Revealed by Bibliometric Network Analyses

open access: yes
Expectation violations occur when there is a discrepancy between expected and perceived events or experiences. Often, however, expectations persist despite disconfirming evidence.
Christiansen, Hanna   +5 more
core   +1 more source

Theoretical expectation of large Seebeck effect in PtAs2 and PtP2 [PDF]

open access: yes
Motivated by a recent observation of good thermoelectric properties in PtSb2, we theoretically study related pyrites in an attempt to seek for a material that overcomes the suppression of the Seebeck coefficient at high temperatures.
27058   +9 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Expectation and variation with a virtual die

open access: yes, 2015
By the time students reach the middle years they have experienced many chance activities\ud based on dice. Common among these are rolling one die to explore the relationship of\ud frequency and theoretical probability, and rolling two dice and summing ...
English, Lyn D., Watson, Jane
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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