Results 111 to 120 of about 2,911,222 (308)

Reward Uncertainty and Expected Value Enhance Generalization of Episodic Memory. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Yue Y   +5 more
europepmc   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

AN EVALUATION OF EXPECTED VALUE AND EXPECTED VALUE-VARIANCE CRITERIA IN ACHIEVING RISK EFFICIENCY IN CROP SELECTION

open access: yes
This article evaluates the performance of expected value and expected value-variance criteria in achieving risk efficiency in crop selection. Results indicate that the expected returns criterion achieves risk efficiency in many situations because of ...
Reid, Donald W., Tew, Bernard V.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Expected Value

open access: yes, 1997
This online, interactive lesson on expected value provides examples, exercises, and applets in which students will explore relationships between the expected value of real-valued random variables and the center of the distribution.
Siegrist, Kyle
core  

General-Purpose Methods for Simulating Survival Data for Expected Value of Sample Information Calculations. [PDF]

open access: yesMed Decis Making, 2023
Vervaart M   +6 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The effects of compliance programs on the expected value of antitrust infringements

open access: yes, 2017
The talk examines the impact of complicance programs on the expected value for antitrust infringements as perceived by undertakings' decision-maker. The conclusion is that, as no clear correlation can be established, the incentivisation of compliance ...
ARENA, AMEDEO
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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