Results 31 to 40 of about 2,833,538 (233)

Re-engineering a nanodosimetry Monte Carlo code into Geant4: software design and first results

open access: yes, 2009
A set of physics models for nanodosimetry simulation is being re-engineered for use in Geant4-based simulations. This extension of Geant4 capabilities is part of a larger scale R&D project for multi-scale simulation involving adaptable, co-working ...
Gargioni, E., Grichine, V., Pia, M. G.
core   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

Co-designing solutions to enhance access and engagement in pediatric telerehabilitation

open access: yesFrontiers in Rehabilitation Sciences, 2023
IntroductionPrior to the COVID-19 pandemic, children's therapy appointments provided by Ontario's publicly-funded Children's Treatment Centre (CTCs) primarily occurred in-person. With COVID-19 restrictions, CTCs offered services via telerehabilitation (e.
Meaghan Reitzel   +14 more
doaj   +1 more source

Improving mental health service users' with medical co-morbidity transition between tertiary medical hospital and primary care services: A qualitative study [PDF]

open access: yes, 2016
BACKGROUND: Mental health service users have high rates of medical co-morbidity but frequently experience problems accessing and transitioning between tertiary medical and primary care services.
Cranwell, K   +2 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

User Experience of the Co-design Research Approach in eHealth: Activity Analysis With the Course-of-Action Framework

open access: yesJMIR Human Factors, 2022
BackgroundThe cocreation of eHealth solutions with potential users, or co-design, can help make the solution more acceptable. However, the co-design research approach requires substantial investment, and projects are not always ...
Melanie Tremblay   +3 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Using experience-based design to understand the patient and caregiver experience with delirium

open access: yesPatient Experience Journal, 2019
Hospital-acquired delirium negatively affects clinical outcomes and the care experience for patients and family caregivers. Following the qualitative methods of experience-based design, we completed observations of hospital units and interviews of ...
Lauren Russ   +5 more
doaj  

Identifying features associated with higher-quality hospital care and shorter length of admission for people with dementia : a mixed-methods study [PDF]

open access: yes, 2020
Background: Concerns have repeatedly been expressed about the quality of inpatient care that people with dementia receive. Policies and practices have been introduced that aim to improve this, but their impact is unclear.
Burns, Alistair   +10 more
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

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