Results 41 to 50 of about 5,969,034 (305)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

“I could be living a totally different life right now”: lived experience and caregiver perspectives on the prevention of eating disorders

Journal of Eating Disorders
Eating disorder prevention is widely acknowledged as a priority for the field. However, little space has been given to investigating how people who have endured the impacts of eating disorders view the subject of prevention.
James Downs, Ellie Smith, Nicky Smith, Suzanne Baker, Helen Missen, Jodie Goodacre, Hannah Hickinbotham, Nicola Hickinbotham, Zoe Hazel, Debbie Taylor, Hope Virgo   +10 more
doaj   +1 more source

Categorizing and Rating Patient Complaints: An Innovative Approach to Improve Patient Experience

Journal of Patient Experience, 2021
The Ombudsman Office at a large academic medical center created a standardized approach to manage and measure unsolicited patient complaints, including methods to identify longitudinal improvements, accounting for volume variances, as well as incident ...
Stephanie Bayer JD, Paul Kuzmickas JD, Adrienne Boissy MD, MA, Susannah L. Rose PhD, MS, Mary Beth Mercer MPH   +4 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Patient Experience: The field and future

, 2017
In an effort to understand the progress and evolution of the field, a self-examination study has been administered to assess contributions to the core knowledge base in the field and to assess the degree to which articles published in Patient Experience ...
Haun, Courtney N., MPH, Wolf, Jason A, PhD, Silvera, Geoffrey A.   +2 more
core   +1 more source

The reported impact of public involvement in biobanks: A scoping review

Health Expectations, 2020
Background Biobanks increasingly employ public involvement and engagement strategies, though few studies have explored their impact. This review aims to (a) investigate how the impact of public involvement in biobanks is reported and conceptualized by ...
Lidia Luna Puerta, Will Kendall, Bethan Davies, Sophie Day, Helen Ward   +4 more
doaj   +1 more source

Identifying sources of patient dissatisfaction when seeking care for a chronic and complex disease

, 2023
Patients’ evaluations of healthcare often rely on patient satisfaction and encounter-specific approaches. Instead, valuable information can be gained by focusing on patient dissatisfaction with healthcare over time.
Harsin, Amanda, Katharine J Head, Rebecca J Bartlett Ellis, Amanda Harsin, Anna K Forster, Bartlett Ellis, Rebecca J, Head, Katharine J, Forster, Anna K., Bartlett Ellis, Rebecca J., Head, Katharine J., Forster, Anna K   +10 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Language matters: discourses of therapeutic optimism and recovery in the treatment of eating disorders

BJPsych Bulletin
Aims and method This article explores how clinical language used to describe long-standing and severe eating disorders shapes treatment experiences and outcomes.
James Downs, Marissa Adams, Anna Carnegie   +2 more
doaj   +1 more source