Results 71 to 80 of about 3,290,256 (312)

Experiments on pattern-based ontology design

open access: yesProceedings of the fifth international conference on Knowledge capture, 2009
This paper addresses the evaluation of pattern-based ontology design through experiments. An initial method for reuse of content ontology design patterns (Content ODPs) was used by the participants during the experiments. Hypotheses considered include the usefulness of Content ODPs for ontology developers, and we additionally study in what respects ...
Eva Blomqvist   +2 more
openaire   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Australian Indigenous Tertiary Studies: A Discussion with Professor David Boud on Experience-Based Learning and the Transformation of University Courses

open access: yesThe Australian Journal of Indigenous Education, 2012
This article critically examines the possibility of using Problem-Based Learning as an approach to teaching and learning and curriculum design in Indigenous studies.
Heidi Norman
doaj   +1 more source

Mindful Learning Experience Facilitates Mastery Experience Through Heightened Flow and Self-Efficacy in Game-Based Creativity Learning

open access: yesFrontiers in Psychology, 2019
This study was performed within the limited framework of computer-game-based educational programs designed to enhance creativity. Furthermore, the utilization of mindful learning and moderators such as flow, mastery experience, and self-efficacy, brings ...
Yu-chu Yeh   +4 more
doaj   +1 more source

Interactive Experiments in Object-Based Retrieval

open access: yes, 2006
Object-based retrieval is a modality for video retrieval based on segmenting objects from video and allowing end-users to use these objects as part of querying. In this paper we describe an empirical TRECVid-like evaluation of object-based search, and compare it with a standard image-based search into an interactive experiment with 24 search topics and
Sav, Sorin Vasile   +4 more
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Development and reliability of a patient experience inventory tool for hospitals

open access: yes, 2020
This study explores the development and reliability testing of the newly developed Patient Experience Inventory for Hospitals (PXI-H). Created as an organizational self-assessment patient experience tool, it guides healthcare leaders in evaluating ...
Nicole Giammarinaro   +7 more
core   +2 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Gamification in Retail: Enhancing Grocery Customer Experience with Location-Based Strategies

open access: yesInternational Journal of Serious Games
This study explores how gamification impacts customer experience in the retail sector emphasizing the need for businesses to differentiate in competitive markets.
Alireza Zandi, Yoones A. Sekhavat
doaj   +1 more source

Home - About - Disclaimer - Privacy