Results 81 to 90 of about 3,290,256 (312)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
, 2019 Standardized patient experience survey instruments play an important role in informing healthcare quality and process improvement. However, any changes in standardized instruments can impact the interpretation, trending, and analysis of patient reported ...
Beamer, Sharon, AuD +9 more
core +2 more sources
Impact of comprehensive teaching mode and trainer experience on teaching effect of basic surgical skill training [PDF]
Jichu yixue yu linchuang, 2021 Objective To study the impact of comprehensive teaching mode and trainer experience on teaching effect of surgical basic technique training. Methods The present study adopted 2×2 factorial design. Seventy surgical interns were randomly assigned to
WANG Chang-jun, LIN Yan, ZHOU Yi-dong, ZHAO Jun, JIANG Ying-zi, LUO Lin-zhi, SUN Qiang
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
A Logical Approach to Experience-Based Reasoning
New Mathematics and Natural Computation, 2017 Experience-based reasoning (EBR) is a paradigm used in almost every human activity as a part of human reasoning. However, EBR has not been seriously studied from a logical viewpoint. This paper will attempt to fill this gap by providing a unified logical approach to EBR. More specifically, this paper first examines EBR and inference rules.
openaire +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Experience-based pedagogical designs for elearning
, 2001 In this paper, we discuss a selection of experience-based pedagogical designs, which stand to make the most of the opportunities afforded by information and communications technology.
Albert Ip (19122499) +1 more
core +1 more source
Pulmonary CirculationPulmonary hypertension (PH) is a progressive condition associated with reduced physical activity and impaired quality of life. While exercise training is now recognised as a safe and beneficial adjunct to PH management, opportunities for supervised ...
Ciara McCormack +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source