Results 61 to 70 of about 2,368 (218)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Verification of a Numerical Simulation Code for Underwater Chain Mooring

Archive of Mechanical Engineering, 2016
Numerical simulation is an economical and effective method in the field of marine engineering. The dynamics of mooring cables has been analysed by a numerical simulation code that was created on a basis of a new element frame.
Zhu Xiangqian, Yoo Wansuk
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

A Compact Model for Interface-Type Self-Rectifying Resistive Memory With Experiment Verification

IEEE Access
Resistive random access memory (RRAM), a new non-volatile memory, enables hardware accelerators based on in-memory computing with improved throughput and energy efficiency, enabling machine learning on-the-fly inference at the edge.
Jin-Woo Kim, Jun-Seok Beom, Hong-Sub Lee, Nam-Seog Kim   +3 more
doaj   +1 more source

Quantifying verification uncertainty by reference data variation

Meteorologische Zeitschrift, 2012
In the framework of a multi-level verification experiment, the impact of different characteristics of verification reference data on NWP-model verification is evaluated.
Theresa Gorgas, Manfred Dorninger
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Sensitivity Analysis and Experimental Verification of Bolt Support Parameters Based on Orthogonal Experiment

Shock and Vibration, 2020
This paper presents a unified supporting parameter optimization procedure for the coupled bolt-rock systems by using the orthogonal experimental methods.
Kun Zhang, Jinpeng Su, Zengkai Liu, Hongyue Chen, Qiang Zhang, Shaoan Sun   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Method of verification of results of individual forecasting of products of radioelectronic facilities for space purposes with the help of cluster analysis algorithms

Физика волновых процессов и радиотехнические системы, 2017
The methodology and algorithm for obtaining verification results are proposed. The algorithm includes five steps: choice of parameters for cluster analysis algorithms, determination of the initial data by the results of the training experiment ...
R.O. Mishanov, M.N. Piganov
doaj