Results 81 to 90 of about 2,951,513 (284)
, 1953 The Oklahoma Agricultural Experiment Station periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University ...
Darlow, A. E., Hawkins, Louis Edward
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Quantifying verification uncertainty by reference data variation
Meteorologische Zeitschrift, 2012 In the framework of a multi-level verification experiment, the impact of different characteristics of verification reference data on NWP-model verification is evaluated.
Theresa Gorgas, Manfred Dorninger
doaj +1 more source
Transient characteristics verification method for DC transformer used in flexible HVDC system
Global Energy Interconnection, 2019 Previous studies have proposed higher requirements for the transient characteristics of a DC transformer used in a flexible high-voltage direct current (HVDC) system to achieve faster sampling speed and meet wider bandwidth requirements of the control ...
Qi Nie +5 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Физика волновых процессов и радиотехнические системы, 2017 The methodology and algorithm for obtaining verification results are proposed. The algorithm includes five steps: choice of parameters for cluster analysis algorithms, determination of the initial data by the results of the training experiment ...
R.O. Mishanov, M.N. Piganov
doaj
Scientific ReportsTo rigorously evaluate the electromechanical-hydraulic coupling performance of a hydraulic excavator’s working device under authentic operating loads, this study presents a field-data-driven co-simulation framework applied to a 20-ton backhoe hydraulic ...
Mei Xin +6 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source