Results 101 to 110 of about 3,019,422 (250)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

The mechanisms of Huangqi Guizhi Wuwu decoction in treating ischaemic stroke based on network pharmacology and experiment verification. [PDF]

Pharm Biol, 2023
Liao W, Wang M, Wu Y, Du J, Li Y, Su A, Zhong L, Xie Z, Gong M, Liang J, Wang P, Liu Z, Wang L.   +12 more
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Research on microfluidics detection chip for ingredients of animal origin in feed

Siliao yanjiu, 2021
The detection chip for ingredients of animal origin in feed was developed based on the 'LAMP+microfluidics' technology. Aiming at the target sequences of 16SrDNA from beef, mutton, pork and chicken, the four kinds of meat primer were designed according ...
Yu-fei CHEN, Liu YANG, Lei WANG
doaj  

Correction: Identification of kukoamine a as an anti-osteoporosis drug target using network pharmacology and experiment verification. [PDF]

Mol Med, 2023
Luo L, Guan Z, Jin X, Guan Z, Jiang Y.
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

User Authentication Using Inner-Wrist Skin Prints: Feasibility and Performance Assessment with Off-the-Shelf Fingerprint Sensor

Sensors
Wrist-worn devices enable new paradigms of implicit and continuous user authentication; however, identifying biometric modalities that combine reliability with practical integrability remains challenging.
Szymon Cygan, Patryk Lamprecht, Jakub Żmigrodzki, Jan Łusakowski-Milencki, Nikolaos Simopulos, Adrian Zarycki, Piotr Muranty   +6 more
doaj   +1 more source

Mechanistic insights into the ameliorative effects of hypoxia-induced myocardial injury by Corydalis yanhusuo total alkaloids: based on network pharmacology and experiment verification. [PDF]

Front Pharmacol, 2023
Qi J, Li H, Yang Y, Sun X, Wang J, Han X, Chu X, Sun Z, Chu L.   +8 more
europepmc   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Identification of kukoamine a as an anti-osteoporosis drug target using network pharmacology and experiment verification. [PDF]

Mol Med, 2023
Luo L, Guan Z, Jin X, Guan Z, Jiang Y.
europepmc   +1 more source