Proteoglycans and Hyaluronan in Normal and Aberrant Lung Development
ABSTRACT Lung development is a tightly regulated process that progresses through five distinct stages: embryonic, pseudoglandular, canalicular, saccular, and alveolar. Each stage is characterized by coordinated cellular interactions and structural changes driven by signals from epithelial, endothelial, and mesenchymal cells.
Andrea Reszegi +4 more
wiley +1 more source
STING‐dependent induction of neutrophilic asthma exacerbation in response to house dust mite
This study investigates whether STING‐induced neutrophilic lung inflammation mimics severe asthma. STING activation during allergic challenge triggers neutrophilic asthma accompanied by a Th1 and pro‐inflammatory cytokine in addition to the Th2 cytokines resulting in an epithelial barrier damage, cell death and self‐dsDNA release with increased mucus ...
Yasmine Messaoud‐Nacer +16 more
wiley +1 more source
Several lines of research indirectly suggest that platelet activating factor (PAF) may intervene in the pathogenesis of extrinsic allergic alveolitis (EAA).
J-L. Pérez-Arellano +5 more
doaj +1 more source
Respiratory Ill‐Health and Welding Exposures: A Canadian Cohort Study
ABSTRACT Introduction Respiratory ill‐health in welders is well documented but without a clear indication of exposures responsible. Methods In a Canadian cohort study of welders and electrical workers, we collected self‐reports of asthma/wheeze and rhinitis at each 6‐monthly contact for up to 5 years.
Jean‐Michel Galarneau +2 more
wiley +1 more source
Bleomycin‐induced acute lung injury but not fibrosis is regulated in WT mice by the presence of radioresistant innate IL‐17A/F‐producing T cells and is exacerbated in IL17af−/− mice. Recombinant IL‐17A/F therapy but not WT bone marrow transplantation ameliorates bleomycin induced acute lung injury in IL17af−/− mice.
Marie T. Moog +9 more
wiley +1 more source
Allergic alveolitis in workers exposed to moulds [PDF]
Autori iznose neke podatke o incidenciji i prevalenciji alergijskog alveolitisa između 500 poljoprivrednika središnjeg dijela zemlje i između 3 000 poljoprivrednika iz sjevernih područja Švedske.
Blomqvist, G. +5 more
core +1 more source
The tiotriasolinantioxidant action upon content of peroxide lipid oxidation products, and antioxidant system ferments activity in guinea-pigs’ pulmonary tissue under conditions of allergic experimental alveolitis development [PDF]
У роботі вивчено коригуючий вплив антиоксиданта тіотріазоліну на вміст у легеневій тканині тварин дієнових кон’югатів, малонового діальдегіду, супероксиддисмутази і каталази при експериментальному алергічному альвеоліті.The work presents the ...
Ковалишин, О.А.
core +2 more sources
We have analyzed the results of investigation of alterations in indices of pro-oxidant (conjugated diene and malondialdehyde) and antioxidant (superoxide dismutase, ceruloplasmin, catalase) systems in guinea pigs’ lungs in experimental allergic ...
Mariana Baida +2 more
doaj +1 more source
Peculiarities of changes prooxidant-antioxidant processes in lungs in conditions of experimental allergic alveolitis and their correction with thiotriazolin [PDF]
У роботі показано, що в динаміці розвитку експериментального алергічного альвеоліту (14-а, 24-а, 34-а і 44-а доби) відбувається поступове збільшення рівня продуктів переоксидного окиснення ліпідів (ПОЛ) в легенях та зростання активності ...
Пасічник, М.А.
core +1 more source
The Endogenous Th17 Response in NO
Severe, glucocorticoid-resistant asthma comprises 5-7% of patients with asthma. IL-17 is a biomarker of severe asthma, and the adoptive transfer of Th17 cells in mice is sufficient to induce glucocorticoid-resistant allergic airway disease.
Suratt, Benjamin T. +45 more
core +2 more sources

