Results 101 to 110 of about 2,558,177 (259)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Joint Behavior of Full-Scale Precast Concrete Pipe Infrastructure: Experimental and Numerical Analysis

open access: yesInfrastructures
This study undertakes a comprehensive experimental and numerical analysis of the structural integrity of buried RC sewerage pipes, focusing on the performance of two distinct jointing materials: cement mortar and non-shrinkage grout.
Abdul Basit   +5 more
doaj   +1 more source

Belief Propagation Algorithm for Portfolio Optimization Problems

open access: yes, 2010
The typical behavior of optimal solutions to portfolio optimization problems with absolute deviation and expected shortfall models using replica analysis was pioneeringly estimated by S. Ciliberti and M. M\'ezard [Eur. Phys. B.
Shinzato, Takashi, Yasuda, Muneki
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Experimental analysis of the tensile behavior of concrete reinforced with Brazilian glass textile

open access: yesRevista ALCONPAT
In this study, the mechanical behavior of concrete structures reinforced with one and two layers of the Brazilian glass textile “AR-360” was verified through direct tensile tests.
Joici Rizzo   +4 more
doaj   +1 more source

Numerical Model and Experimental Analysis of the Thermal Behavior of Electric Radiant Heating Panels

open access: yesApplied Sciences, 2018
Electric radiant heating panels are frequently selected during the design phase of residential and industrial heating systems, especially for retrofit of existing buildings, as an alternative to other common heating systems, such as radiators or air ...
Giovanni Ferrarini   +6 more
doaj   +1 more source

Theoretical aspects of high energy elastic nucleon scattering [PDF]

open access: yes, 2009
The eikonal model must be denoted as strongly preferable for the analysis of elastic high-energy hadron collisions. The given approach allows to derive corresponding impact parameter profiles that characterize important physical features of nucleon ...
Kaspar, Jan   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Experimental Analysis and Numerical Modelling of the Mechanical Behavior of a Sisal-Fiber-Reinforced Geopolymer

open access: yesApplied Sciences
The present paper is devoted to the proposal of appropriate numerical modelling able to provide a suitable description of the mechanical behavior of a composite geopolymer. Reference is made to a natural sisal-fiber-reinforced geopolymer.
Salvatore Benfratello   +4 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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