Results 101 to 110 of about 1,391,396 (316)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Observing Behavior: Effects of Rate and Magnitude of Primary Reinforcement
, 2002 Four experiments examined the free-operant observing behavior of rats. In Experiment 1, observing was a bitonic function of random-ratio schedule requirements for the primary reinforcer.
Shahan, Timothy A.
core +1 more source
Behavioral Cusps: A Developmental and Pragmatic Concept for Behavior Analysis [PDF]
, 1997 Article on behavioral cusps and a developmental and pragmatic concept for behavior ...
Rosales-Ruiz, Jesus +1 more
core +1 more source
FOX DOMESTICATION: MOLECULAR MECHANISMS INVOLVED IN SELECTION FOR BEHAVIOR
Вавиловский журнал генетики и селекции, 2014 Although animal domestication has enjoyed the attention of geneticists and evolutionary biologists since Darwin’s times, the focal question about genetic basis of this process has not been duly considered.
L. N. Trut +4 more
doaj
Advances in Materials Science and Engineering, 2018 Shear performance of plain UHPC (ultrahigh-performance concrete) construction joints is studied in both experimental and analytical ways. In push-off tests, three different contact surfaces of the construction joint were considered, while the case ...
Hyun-O. Jang +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Risk Dominance Selects the Leader: An Experimental Analysis [PDF]
, 2000 We perform an experimental analysis to test whether the risk dominance prediction is supported by the behavior of laboratory agents, in a 2X 2 coordination game whose equilibria are not Pareto ranked.
García-Fontes, Walter +5 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Effects of Alternative Reinforcement on Human Behavior: The Source Does Matter
, 2003 Competing theories regarding the effects of delivering periodic response-independent reinforcement (more accurately, response-independent points exchanged for money) on a baseline rate of behavior were evaluated in human subjects. Contiguity theory holds
Perone, Michael +3 more
core +1 more source