Results 121 to 130 of about 6,369,773 (275)

Improving enteral nutrition in patients requiring neurological intensive care unit care: A retrospective study on a novel bedside nasointestinal tube placement technique

Nutrition in Clinical Practice, EarlyView.
Abstract Background This study aimed to develop and assess a bedside nasojejunal tube placement technique designed for resource‐limited settings to address the specific challenges of enteral nutrition (EN) delivery in neurocritical care patients, particularly those at high risk of reflux and aspiration. The technique sought to overcome the drawbacks of
Niuchenglin, Liujuan, Zhushuibing, Dingyuanliang, Yutianhao, Shiguangling   +5 more
wiley   +1 more source

Auto-Reactive Th17-Cells Trigger Obsessive-Compulsive-Disorder Like Behavior in Mice With Experimental Autoimmune Encephalomyelitis

Frontiers in Immunology, 2018
Th17-lymphocytes are well known for their deleterious role in autoimmunity. But does the notoriety of this repertoire extend beyond autoimmunity? In the present study we employed experimental autoimmune encephalomyelitis as model system to study the role
Ravi Kant, Ravi Kant, Shweta Pasi, Shweta Pasi, Avadhesha Surolia, Avadhesha Surolia   +5 more
doaj   +1 more source

Myelin Oligodendrocyte Glycoprotein (MOG35-55) Induced Experimental Autoimmune Encephalomyelitis (EAE) in C57BL/6 Mice

Journal of Visualized Experiments, 2014
Multiple sclerosis is a chronic neuroinflammatory demyelinating disorder of the central nervous system with a strong neurodegenerative component. While the exact etiology of the disease is yet unclear, autoreactive T lymphocytes are thought to play a ...
S. Bittner, A. Afzali, H. Wiendl, S. Meuth   +3 more
semanticscholar   +1 more source

Innate immune activation in experimental autoimmune myocarditis [PDF]

, 2007
Dilated cardiomyopathy (DCM) is a leading cause of heart failure and frequently results from postinfectious autoimmunity. Its pathophysiology is modeled by experimental autoimmune myocarditis (EAM), a CD4+ T-cell mediated murine model of ...
Marty, René Roger
core   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Interferon-¿ regulates oxidative stress during experimental autoimmune encephalomyelitis

, 2002
Neurobiology, experimental autoimmune encephalomyelitis IFN-d, multiple sclerosis, neurodegeneration, oxidative ...
Saez-Torres, I., Montalban, X., Espejo, C., Hidalgo, Juan, Penkowa, Milena, Garcia, A., Martinez-Caceres, E.M.   +6 more
core   +1 more source

Targeting microglia-Th17 feed-forward loop to suppress autoimmune neuroinflammation

Journal of Neuroinflammation
Microglia and Th17 cells are the major immunopathogenic cells in multiple sclerosis and its animal model of immune aspects, experimental autoimmune encephalomyelitis (EAE).
Jun Xiao, Zihan Meng, Yao Lu, Zongchang Nie, Yujie Liu, Zhi Yao, Yingchi Zhang, Long Li   +7 more
doaj   +1 more source

Development of IL-17A-associated autoimmunity [PDF]

, 2010
Autoimmunity results from a breakdown in tolerance to self-antigens. Interleukin-17A (IL-17A) is a cytokine that has been implicated in the development of certain autoimmune disorders, notably multiple sclerosis and its mouse model experimental ...
Hornsby, E.
core  

The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders

Brain Pathology, EarlyView.
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu, Yoshiki Takai, Naoya Yamazaki, Sarah Brandl, Katharina M. Mair, Thibault Bouderlique, Maria Eleni Kastriti, Igor Adameyko, Romana Höftberger, Markus Reindl, Jan Bauer, Monika Bradl   +11 more
wiley   +1 more source

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source