Results 191 to 200 of about 49,920 (245)

Targeted lipidomics dataset of central nervous system and plasma from mice with experimental autoimmune encephalomyelitis. [PDF]

Data Brief
Lötsch J, Tegder I, de Bruin N, Thomas D, Geisslinger G.   +4 more
europepmc   +1 more source

Therapeutic potential of S-nitrosoglutathione reductase inhibitor in B cell-driven experimental autoimmune encephalomyelitis. [PDF]

J Neuroimmunol
Won J, Kim J, Qiao F, Singh AK, Singh I.
europepmc   +1 more source

Nalmefene enhances the remyelinating ability of nalfurafine when administered therapeutically at very low doses during experimental autoimmune encephalomyelitis. [PDF]

Clin Transl Immunology
Denny L, Robichon K, Templeton N, Kiernan M, Prisinzano TE, Kivell BM, La Flamme AC.   +6 more
europepmc   +1 more source

Attenuating the experimental autoimmune encephalomyelitis model improves preclinical evaluation of candidate multiple sclerosis therapeutics. [PDF]

Animal Model Exp Med
Lim VJT, Murphy MJ, Penrose WS, Warr C, Keightley MC, Orian JM.   +5 more
europepmc   +1 more source

Differences of the 6N and 6J Substrains of C57BL/6 Mice in the Development of Experimental Autoimmune Encephalomyelitis. [PDF]

MedComm (2020)
Álvarez-López AI, Ponce-España E, Cruz-Chamorro I, Santos-Sánchez G, Bejarano I, Álvarez-Sánchez N, Lardone PJ, Carrillo-Vico A.   +7 more
europepmc   +1 more source

Astrocytic-OTUD7B ameliorates murine experimental autoimmune encephalomyelitis by stabilizing glial fibrillary acidic protein and preventing inflammation. [PDF]

Nat Commun
Harit K, Yi W, Jeron A, Schmidt J, Beckervordersandforth R, Wyler E, Manukyan A, Deckert M, Radbruch H, Conrad T, Altmüller J, Landthaler M, Wang X, Nishanth G, Schlüter D.   +14 more
europepmc   +1 more source

Experimental Autoimmune Encephalomyelitis [PDF]

, 1995
Experimental Autoimmune Encephalomyelitis (EAE) is the prototype for cell-mediated autoimmune disease in general, and is the best animal model of human CNS inflammatory demyelinating disease. It has three forms, which vary in clinical course and neuropathology: acute EAE, hyperacute EAE and chronic relapsing EAE.
Pender, Michael P.
core   +4 more sources

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Experimental Autoimmune Encephalomyelitis in the Mouse

Current Protocols, 2021
AbstractThis article details the materials and methods required for both active induction and adoptive transfer of experimental autoimmune encephalomyelitis (EAE) in the SJL mouse strain using intact proteins or peptides from the two major myelin proteins: proteolipid protein (PLP) and myelin basic protein (MBP).
Collin, Laaker, Martin, Hsu, Zsuzsanna, Fabry, Stephen D, Miller, William J, Karpus   +4 more
openaire   +2 more sources

Microbiome Methods in Experimental Autoimmune Encephalomyelitis

Current Protocols, 2021
AbstractMicrobiome composition studies are increasingly shedding light on animal models of disease. This paper describes a protocol for analyzing the gut microbiome composition prior to and after the induction of mice to experimental autoimmune encephalomyelitis (EAE), the principal animal model of the human neuroinflammatory demyelinating disease ...
David P, Daberkow, Kristina, Hoffman, Hannah M, Kohl, Tyrel, Long, Trevor O, Kirby, Javier, Ochoa-Repáraz   +5 more
openaire   +2 more sources

Experimental Autoimmune Encephalomyelitis

2004
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelinating disease of the central nervous system that is induced in laboratory animals by the generation of an immune response against myelin epitopes. It has been used as a prototype of Th1- and/or Th17-driven, organ-specific autoimmunity and as a model for the human disease ...
Praveen, Rao, Benjamin M, Segal
openaire   +4 more sources