Results 101 to 110 of about 1,555 (179)

Protective Effect of Intravitreal Administration of Tresperimus, an Immunosuppressive Drug, on Experimental Autoimmune Uveoretinitis

, 2011
PURPOSE: To test the efficiency of locally administrated tresperimus in experimental autoimmune uveoretinitis (EAU). METHODS: EAU was induced in Lewis rats by S-antigen (S-Ag) immunization.
Brigitte Goldenberg, Leroux les Jardins, G., Annat, J., Yvonne de Kozak, Naud, M.C., Marie-Christine Naud, Francine Behar-Cohen, Behar-Cohen, F., Bousquet, E., Elodie Bousquet, Lebreton, L., Luc Lebreton, Besson-Lescure, B., Goldenberg, B., Camelo, S., Bernadette Besson-Lescure, Serge Camelo, Jocelyne Annat, de Kozak, Y., Guillaume Leroux les Jardins   +19 more
core   +1 more source

Photopic light-mediated down-regulation of local α_1A-adrenergic signaling protects blood-retina barrier in experimental autoimmune uveoretinitis. [PDF]

Sci Rep, 2019
Stofkova A, Kamimura D, Ohki T, Ota M, Arima Y, Murakami M.   +5 more
europepmc   +1 more source

Role of T-cell receptor V beta 8.3 peptide vaccine in the prevention of experimental autoimmune uveoretinitis

, 2006
T-cell receptor (TCR) plays an important role in the development of autoimmune diseases. Recently, it was reported that immunization of animals with TCR peptide derived from the pathogenic cells could prevent autoimmune diseases.
Jin, H.L., Wu, C.Y., Zhang, R., Yang, Pei-zeng, Gao, Yang, Kijlstra, Aize, Huang, X., Zhou, Hong-yan, Li, Bing, Zhou, H., Gao, Y., Huang, Xiang-kun, Yang, P.Z., Li, B., Zhu, L., Jin, Hao-li, Zhu, Lian-xiang, Zhang, Rui, Wu, Chang-you, Kijlstra, A.   +19 more
core  

An essential role for death receptor 3 in experimental autoimmune uveoretinitis. [PDF]

Ocul Immunol Inflamm, 2012
Calder CJ, Wang EC.
europepmc   +1 more source

Kinetics of apoptotic cells in experimental autoimmune uveoretinitis.

Investigative ophthalmology & visual science, 2000
To investigate the role of apoptosis in immunopathogenic mechanisms of experimental autoimmune uveoretinitis (EAU), the kinetics of apoptotic cells and expression of Fas and Fas ligand (FasL) in the eye with EAU were studied.Male inbred Lewis rats were immunized with S-antigen (40 microg/rat), and eyes were examined to detect apoptotic cells on days 1,
J, Sueda, N, Hikita, M, Mochizuki, A, Jimi, M, Kojiro   +4 more
openaire   +1 more source

Ultrastructural pathology of experimental autoimmune uveitis: Quantitative evidence of activation and possible high endothelial venule-like changes in retinal vascular endothelium

, 1992
BACKGROUND: Experimental autoimmune uveitis (EAU) is a highly organ-specific autoimmune disease in which the target is the retinal photoreceptors. It is well recognized as a model of uveoretinitis in humans.
Forrester, J. V., Dua, H. S., Steptoe, R. J., McMenamin, P. G.   +3 more
core  

Maturation-resistant dendritic cells ameliorate experimental autoimmune uveoretinitis. [PDF]

Immune Netw, 2011
Oh K, Kim YS, Lee DS.
europepmc   +1 more source

Inhibition of experimental autoimmune uveoretinitis by oral administration of S-antigen and synthetic peptides.

, 1992
S-Antigen, a photoreceptor cell protein, is highly efficient in inducing experimental autoimmune uveoretinitis (EAU), a severe inflammation of the uveal tract and retina of the eye. S-Antigen and six synthetic peptides, all of which correspond to known T-
Donoso, L A, Vrabec, T R, Dua, H S, Gregerson, D S   +3 more
core  

Amelioration of experimental autoimmune uveoretinitis by aldose reductase inhibition in Lewis rats. [PDF]

Invest Ophthalmol Vis Sci, 2011
Yadav UC, Shoeb M, Srivastava SK, Ramana KV.   +3 more
europepmc   +1 more source

Longitudinal Intravital Imaging of the Retina Reveals Long-term Dynamics of Immune Infiltration and Its Effects on the Glial Network in Experimental Autoimmune Uveoretinitis, without Evident Signs of Neuronal Dysfunction in the Ganglion Cell Layer. [PDF]

Front Immunol, 2016
Bremer D, Pache F, Günther R, Hornow J, Andresen V, Leben R, Mothes R, Zimmermann H, Brandt AU, Paul F, Hauser AE, Radbruch H, Niesner R.   +12 more
europepmc   +1 more source