Mucosal administration of α-fodrin inhibits experimental Sjögren's syndrome autoimmunity [PDF]
Introduction alpha-Fodrin is an autoantigen in Sjogren's syndrome. We hypothesized that mucosal administration of alpha-fodrin might prevent the disease.
Jing He, Jinxia Zhao, Zhanguo Li
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Apoptosis of infiltrating cells in experimental autoimmune uveoretinitis.
To investigate the cellular phenotype and apoptosis of infiltrating cells involved in experimental autoimmune uveoretinitis (EAU).Immunohistochemical staining and in situ apoptosis staining were performed using monoclonal antibodies to monocytes and macrophages (ED1), major histocompatibility complex (MHC) class-II antigen (OX6), T lymphocytes (R73 ...
Yang, P.Z. +5 more
openaire +2 more sources
Depletion of Retinal Dopaminergic Activity in a Mouse Model of Rod Dysfunction Exacerbates Experimental Autoimmune Uveoretinitis: A Role for the Gateway Reflex. [PDF]
Stofkova A +7 more
europepmc +1 more source
Clinical effect of IRT-5 probiotics on immune modulation of autoimmunity or alloimmunity in the eye [PDF]
Background: Although the relation of the gut microbiota to a development of autoimmune and inflammatory diseases has been investigated in various animal models, there are limited studies that evaluate the effect of probiotics in the autoimmune eye ...
Choi, S.H. +9 more
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Cytokine Expression by Inflammatory Cells Obtained from the Spinal Cords of Lewis Rats with Experimental Autoimmune Encephalomyelitis Induced by Inoculation with Myelin Basic Protein and Adjuvants [PDF]
Inflammatory cells were obtained from the spinal cords of rats with acute experimental autoimmune encephalomyelitis EAE induced by inoculation with myelin basic protein MBP and adjuvants. Reverse transcriptase-polymerase chain reaction RT-PCR was used to
Ando +59 more
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Reduced experimental autoimmune encephalomyelitis after intranasal and oral administration of recombinant lactobacilli expressing myelin antigen [PDF]
Oral administration of autoantigens is a safe and convenient way to induce peripheral T-cell tolerance in autoimmune diseases like multiple sclerosis (MS).
Boersma, W.G. (Wim) +8 more
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PurposeInflammation is involved in the pathogenesis of diabetes, however the impact of diabetes on organ-specific autoimmune diseases remains unexplored.
Masaru Takeuchi +6 more
doaj +1 more source
Recruiting specialized macrophages across the borders to restore brain functions [PDF]
Aunque es bien aceptado que el sistema nervioso central tiene un privilegio inmune protegido por la barrera hematoencefálica (BBB) y mantenido por la glía, también se sabe que en condiciones homeostáticas, las células inmunes periféricas son capaces de ...
Corraliza Generelo, Inés María
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Cytokine Profiles in Toxoplasmic and Viral Uveitis [PDF]
BackgroundUveitis is a major cause of visual impairment throughout the world. Analysis of cytokine profiles in aqueous humor specimens may provide insight into the physiopathological processes that underly retinal damage in this context MethodsUsing a ...
Abdelrahman, Tamer +14 more
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Glatiramer acetate treatment does not modify the clinical course of (NZB × BXSB)F1 lupus murine model [PDF]
Glatiramer acetate (GA, copolymer-1, Copaxone®), a therapy approved for treatment of multiple sclerosis (MS), prevents and reverses experimental autoimmune encephalomyelitis, the animal model of MS.
Benkhoucha, Mahdia +5 more
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