Results 91 to 100 of about 1,555 (179)

TNFR1-Dependent Regulation of Myeloid Cell Function in Experimental Autoimmune Uveoretinitis

, 2009
Experimental autoimmune uveoretinitis (EAU) is an autoimmune disease induced in mice, which involves the infiltration of CD11b+ macrophages and CD4+ T cells into the normally immune privileged retina.
Raveney, BJE, Dick, AD, Copland, DA, Nicholson, LB   +3 more
core   +1 more source

Autoimmune uveitis attenuated in diabetic mice through imbalance of Th1/Th17 differentiation via suppression of AP-1 signaling pathway in Th cells

Frontiers in Immunology
PurposeInflammation is involved in the pathogenesis of diabetes, however the impact of diabetes on organ-specific autoimmune diseases remains unexplored.
Masaru Takeuchi, Yoshiaki Nishio, Hideaki Someya, Tomohito Sato, Akihiko Yoshimura, Masataka Ito, Kozo Harimoto   +6 more
doaj   +1 more source

A novel pathogenic RBP-3 peptide reveals epitope spreading in persistent experimental autoimmune uveoretinitis

, 2015
Experimental autoimmune uveoretinitis (EAU) in the C57BL/6J mouse is a model of non-infectious posterior segment intraocular inflammation that parallels clinical features of the human disease.
Dick, Andrew D, Andrew D. Dick, Khera, Tarnjit K, Crawford, Gemma L, Nicholson, Lindsay B, Madeleine L. Stimpson, Lindsay B. Nicholson, Boldison, Joanne, Tarnjit K. Khera, Stimpson, Madeleine L, Joanne Boldison, Copland, David A, Gemma L. Crawford, David A. Copland   +13 more
core   +1 more source

Experimental autoimmune uveoretinitis and pinealitis induced by interphotoreceptor retinoid-binding protein and S-antigen: induction of intraretinal and subretinal neovascularization

, 1990
Experimental autoimmune uveoretinitis (EAU) and pinealitis were induced in Lewis rats following hind foot pad injection of interphotoreceptor retinoid-binding protein (IRBP) or S-antigen. A comparison is made in this study of the in vivo and histological
Almahdawi, S., McGettrick, P.M., Lee, W.R., Shallal, A., Converse, C.A., Graham, D.I.   +5 more
core  

Circulating immune complexes may play a regulatory and pathogenic role in experimental autoimmune uveoretinitis

, 1992
SUMMARY We compared the time course of changes in serum levels of circulating immune complexes (CICs) and of IgG antibody after sensilization of albino Lewis and pigmented Lister strain rats with uveitogenic (retinal S-antigen) and non ...
D C DUMONDE, M R STANFORD, A G A COOMBES, E KASP, E BROWN   +4 more
core   +1 more source

Cannabinoids for the control of experimental multiple sclerosis

, 2010
PhDThere have been numerous studies reporting that cannabinoids, both exogenous and endogenous, have a potential beneficial function during incidences of neurological damage.
Pryce, Gareth
core  

Correlation of optical coherence tomography with clinical and histopathological findings in experimental autoimmune uveoretinitis

, 2011
Optical coherence tomography (OCT) is becoming the state-of-the-art method for the non-invasive imaging of a variety of ocular diseases. The aim of this study was to assess the application of OCT for the in vivo monitoring and follow-up of pathological ...
Hein, K., Sarah K. Williams, Diem, R., Ricarda Diem, Sättler, M. B., Williams, S. K., Muriel B. Sättler, Katharina Hein, Bähr, M., Mathias Bähr, Gadjanski, I., Ivana Gadjanski   +11 more
core   +1 more source

The study of experimental autoimmune uveoretinitis (EAU) induction in mice [PDF]

, 1999
This study has demonstrated that a highly reproducible model of experimental autoimmune uveoretinitis (EAU) can be achieved in the BIO.RIII mice using a human interphotoreceptor retinoid binding protein peptide corresponding to amino acid residues 161 ...
Hankey, Deborah Jayne Rachel
core  

Contribution of CD4(+)CD25(+) T Cells to the Regression Phase of Experimental Autoimmune Uveoretinitis

, 2010
PURPOSE. To investigate the role of CD4(+)CD25(+) Treg cells in the development of experimental autoimmune uveoretinitis (EAU). METHODS. EAU was induced in B10RIII mice by immunization with IRBP161-180 in complete Freund's adjuvant and evaluated ...
Yang, Peizeng, Ren, Xiangrong, Du, Liping, Sun, Min, Zhou, Hongyan, Kijlstra, Aize   +5 more
core   +1 more source

Oral Delivery of ACE2/Ang-(1–7) Bioencapsulated in Plant Cells Protects Against Experimental Uveitis and Autoimmune Uveoretinitis

, 2014
Hyperactivity of the renin-angiotensin system (RAS) resulting in elevated Angiotensin II (Ang II) contributes to all stages of inflammatory responses including ocular inflammation. The discovery of angiotensin-converting enzyme 2 (ACE2) has established a
Shil, Pollob K., Verma, Amrisha, Li, Qiuhong, Kwon, Kwang-Chul, Daniell, Henry, Zhu, Ping   +5 more
core   +2 more sources