Results 81 to 90 of about 1,555 (179)

Effects of Mesenchymal Stem Cell-Derived Exosomes on Experimental Autoimmune Uveitis

Scientific Reports, 2017
We previously demonstrated that mesenchymal stem cells (MSCs) ameliorated experimental autoimmune uveoretinitis (EAU) in rats. Recently, MSC-derived exosomes (MSC-Exo) were thought to carry functions of MSCs.
Lingling Bai, Hui Shao, Hongxing Wang, Zhihui Zhang, Chang Su, Lijie Dong, Bo Yu, Xiteng Chen, Xiaorong Li, Xiaomin Zhang   +9 more
doaj   +1 more source

A simple method for in vivo labelling of infiltrating leukocytes in the mouse retina using indocyanine green dye

Disease Models & Mechanisms, 2015
We have developed a method to label and image myeloid cells infiltrating the mouse retina and choroid in vivo, using a single depot injection of indocyanine green dye (ICG).
Dawn A. Sim, Colin J. Chu, Senthil Selvam, Michael B. Powner, Sidath Liyanage, David A. Copland, Pearse A. Keane, Adnan Tufail, Catherine A. Egan, James W. B. Bainbridge, Richard W. Lee, Andrew D. Dick, Marcus Fruttiger   +12 more
doaj   +1 more source

PD-1 Targeted Nanoparticles Inhibit Activated T Cells and Alleviate Autoimmunity via Suppression of Cellular Energy Metabolism Mediated by PKM2

International Journal of Nanomedicine, 2022
Zhangluxi Liu, Jing Xu, Hongxi Li, Jia Shu, Guannan Su, Chunjiang Zhou, Peizeng Yang The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing Branch of National Clinical ...
Liu Z, Xu J, Li H, Shu J, Su G, Zhou C, Yang P   +6 more
doaj  

IgG subclass of anti-EsteD and anti- brain-type creatine kinase antibodies in experimental autoimmune uveoretinitis mice were determined by ELISA

, 2011
Concentrations of anti-EsteD and anti- brain-type creatine kinase (BB-CK) IgG1 antibodies in all tested serum samples of experimental autoimmune uveoretinitis were much higher than those of anti-EsteD and anti-BB-CK IgG2a antibodies.
Yoshihiko Usui (93142), Hiroshi Nakamura (8789), Kazuo Yudoh (8787), Masaru Takeuchi (93147), Yoko Okunuki (93141), Kayo Masuko (68495), Hiroshi Goto (93145), Kusuki Nishioka (1918), Takeshi Kezuka (93143), Takaaki Hattori (93144), Tomohiro Kato (1919), Masahiko Usui (93146)   +11 more
core   +1 more source

Apoptosis of infiltrating cells in experimental autoimmune uveoretinitis.

Chinese medical journal, 2000
To investigate the cellular phenotype and apoptosis of infiltrating cells involved in experimental autoimmune uveoretinitis (EAU).Immunohistochemical staining and in situ apoptosis staining were performed using monoclonal antibodies to monocytes and macrophages (ED1), major histocompatibility complex (MHC) class-II antigen (OX6), T lymphocytes (R73 ...
Yang, P.Z., Herzberg, N.H., Zhou, H.Y., Broersma, L., de Smet, M.D., Kijlstra, A.   +5 more
openaire   +2 more sources

Effect of lymphocytic infiltration on the blood-retinal barrier in experimental autoimmune uveoretinitis

, 1992
SUMMARY Using an experimental model of autoimmune uveoretinitis, we have examined the relationship of T cell infiltration in the retina to blood-retinal barrier (BRB) breakdown.
S LIGHTMAN, J GREENWOOD
core   +1 more source

Direct detection of reactive nitrogen species in experimental autoimmune uveitis. [PDF]

, 2007
PURPOSE: Demonstrate unequivocally the generation of nitric oxide in experimental autoimmune uveoretinitis by electron spin resonance spectroscopy (ESR) using ferrous iron complex of N-methyl-D-glucamine dithiocarbamate, (MGD)(2)-Fe(2+), as a spin trap ...
Zamir, E, Rao, NA, Wu, GS, Sevanian, A, Bae, SR, Schultz, BE   +5 more
core   +1 more source

Depletion of Retinal Dopaminergic Activity in a Mouse Model of Rod Dysfunction Exacerbates Experimental Autoimmune Uveoretinitis: A Role for the Gateway Reflex. [PDF]

Int J Mol Sci, 2021
Stofkova A, Zloh M, Andreanska D, Fiserova I, Kubovciak J, Hejda J, Kutilek P, Murakami M.   +7 more
europepmc   +1 more source

CCR2 and CX3CR1 in monocyte trafficking in experimental autoimmune uveoretinitis

, 2008
We used Experimental Autoimmune Uveoretinitis (EAU) as a model system to investigate the involvement of CCR2 and CX3CR1 in regulating the trafficking and function of monocytes and microglia in an autoimmune context. METHODS: W.T.
Dagkalis, Athanasios
core  

Lipopolysaccharide-activated IL-10-secreting dendritic cells suppress experimental autoimmune uveoretinitis by MHCII-dependent activation of CD62L-expressing regulatory T cells.

, 2008
Dendritic cells (DC) are key regulators of immune responses. Mature DC are traditionally considered to be immunogenic, although there is accumulating evidence that they can also be tolerogenic and induce Ag-specific regulatory T cells (Tregs).
Cornall, Richard, Biester, S, Lau, AW, Forrester, JV, Cornall, RJ   +4 more
core   +1 more source