Results 1 to 10 of about 7,673,385 (305)
Differential Protein Content between Fresh and Freeze-Dried Plasma Rich in Growth Factors Eye Drops
Biomolecules, 2022 The purpose of this study was to analyze the proteomic composition of plasma rich in growth factors eye drops (PRGF) in comparison to lyophilized PRGF eye drops (PRGF lyo).
Eduardo Anitua +5 more
doaj +1 more source
Nature Communications, 2017 Aggregation of eye lens proteins leads to cataracts, a major cause of blindness. Here the authors use solid state NMR to probe the structure of γD-crystallin eye lens proteins aggregates, which are found to retain a native-like conformation.
Jennifer C. Boatz +4 more
doaj +1 more source
A Drosophila ortholog of the human MRJ modulates polyglutamine toxicity and aggregation
Neurobiology of Disease, 2006 In the Drosophila eye, proteins with an expanded polyglutamine (polyQ) tract form nuclear and cytoplasmic inclusions and produce cytotoxicity, demonstrated as loss of eye pigmentation and structural integrity.
Zahra Fayazi +5 more
doaj +1 more source
Disease Models & Mechanisms, 2020 To gain a comprehensive view of the changes in host gene expression underlying Zika virus (ZIKV) pathogenesis, we performed whole-genome RNA sequencing (RNA-seq) of ZIKV-infected Drosophila adult flies.
Sneh Harsh +4 more
doaj +1 more source
BMC Veterinary Research, 2019 Background Organophosphate pesticides-OP-, like malathion, can alter the normal functioning of neuro-endocrine systems (e.g., hypothalamus-pituitary-thyroid-HPT- axis), and to interfere on the thyroidal homeostasis.
Juan B. Ortiz-Delgado +2 more
doaj +1 more source
Intravitreal hydrogels for sustained release of therapeutic proteins.
Journal of Controlled Release, 2020 This review highlights how hydrogel formulations can improve intravitreal protein delivery to the posterior segment of the eye in order to increase therapeutic outcome and patient compliance.
Blessing C. Ilochonwu +3 more
semanticscholar +1 more source
Bone Morphogenetic Proteins and Their Receptors in the Eye
Experimental Biology and Medicine, 2007 The human genome encodes at least 42 different members of the transforming growth factor-β superfamily of growth factors. Bone morphogenetic proteins (BMPs) are the largest subfamily of proteins within the transforming growth factor-β superfamily and are involved in numerous cellular functions including development, morphogenesis, cell proliferation ...
Robert J, Wordinger, Abbot F, Clark
openaire +2 more sources
Dry Eye: A Protein Conformational Disease
Investigative Ophthalmology & Visual Science, 2015 The purpose of this study was to determine whether aqueous-deficient dry eyes (ADDE) is a protein conformational disease. Up to now the therapeutic regimen has been based on empirical results, but these observations may unfold new theranostic approaches for ADDE management.Fifty ADDE patients and 46 healthy volunteers were recruited.
Mohammad, Azharuddin +4 more
openaire +2 more sources
Conserved chemosensory proteins in the proboscis and eyes of Lepidoptera [PDF]
International Journal of Biological Sciences, 2016 Odorant-binding proteins (OBPs) and chemosensory proteins (CSPs) are endowed with several different functions besides being carriers for pheromones and odorants. Based on a previous report of a CSP acting as surfactant in the proboscis of the moth Helicoverpa armigera, we revealed the presence of orthologue proteins in two other moths Plutella ...
Zhu, Jiao +8 more
openaire +2 more sources
Aptamer/AuNP Biosensor for Colorimetric Profiling of Exosomal Proteins
Angewandte Chemie, 2017 Exosomes constitute an emerging biomarker for cancer diagnosis since they carry multiple proteins reflecting the origins of parent cells. Assessing exosome surface proteins provides a powerful means of identifying a combination of biomarkers for cancer ...
Ying Jiang +6 more
semanticscholar +1 more source