Results 21 to 30 of about 247,181 (310)
Immunological and antimicrobial molecules in human tears: a review and preliminary report*
African Vision and Eye Health, 2012 The human tear film is a multi-layered and chemically complex structure, which performs numerous functions relating to the health of the corneal surface.
R. Schnetler +2 more
doaj +1 more source
Membranes, 2021 α-crystallin is a major protein found in the mammalian eye lens that works as a molecular chaperone by preventing the aggregation of proteins and providing tolerance to stress in the eye lens.
Raju Timsina, Laxman Mainali
doaj +1 more source
eLife, 2020 Phosphoinositides (PI) are key regulators of cellular organization in eukaryotes and genes that tune PI signaling are implicated in human disease mechanisms.
Deepti Trivedi +8 more
doaj +1 more source
Early stages of retinal development depend on Sec13 function [PDF]
, 2013 ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Feng, Yi +7 more
core +1 more source
Journal of Ophthalmic Inflammation and Infection, 2021 Background To identify candidate tear fluid biomarkers in patients with unilateral acute anterior uveitis (AAU) that can aid in the differentiation between these patients and patients with bacterial keratitis or healthy controls.
Jon Roger Eidet +6 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2022 Pseudoexfoliation (PXF) is characterized by the accumulation of the exfoliative material in the eye and high rates of blindness if left untreated.
Prity Sahay +5 more
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Bird Eye View of Protein Subcellular Localization Prediction
, 2020 Proteins are made up of long chain of amino acids that perform a variety of functions in different organisms. The activity of the proteins is determined by the nucleotide sequence of their genes and by its 3D structure.
Sandeep Kumar Dhanda, Ravindra Kumar
core +1 more source
Molecular genetic analysis of a "sine oculis" enhancer and the "leventina" gene as a model system to study human macular degeneration in "Drosophila" [PDF]
, 2004 The leventina gene as a model system to study human macular degeneration in Drosophila. Age-related macular degeneration (AMD) is one of the most frequent reasons for blindness of the elderly people and accounts for approximately 50% of registered ...
Pauli, Tobias Samuel
core +1 more source
Nature Communications, 2017 Aggregation of eye lens proteins leads to cataracts, a major cause of blindness. Here the authors use solid state NMR to probe the structure of γD-crystallin eye lens proteins aggregates, which are found to retain a native-like conformation.
Jennifer C. Boatz +4 more
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A Drosophila ortholog of the human MRJ modulates polyglutamine toxicity and aggregation
Neurobiology of Disease, 2006 In the Drosophila eye, proteins with an expanded polyglutamine (polyQ) tract form nuclear and cytoplasmic inclusions and produce cytotoxicity, demonstrated as loss of eye pigmentation and structural integrity.
Zahra Fayazi +5 more
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