Results 41 to 50 of about 7,673,385 (305)

Amniotic membrane extract and eye drops: a review of literature and clinical application

open access: yesClinical Ophthalmology, 2018
The amniotic membrane (AM) has a long history of use in the treatment of various diseases of the ocular surface. It contains pluripotent cells, highly organized collagen, anti-fibrotic and anti-inflammatory cytokines, immune-modulators, growth factors ...
M. Murri   +5 more
semanticscholar   +1 more source

Recent advances of exosomes in immune-mediated eye diseases

open access: yesStem cell research & therapeutics, 2019
Exosomes, nanosized extracellular vesicles of 30–150 nm, are shed by almost all cell types. Bearing proteins, lipids, RNAs, and DNAs, exosomes have emerged as vital biological mediators in cell-to-cell communication, affecting a plethora of physiological
Na Li   +5 more
semanticscholar   +1 more source

A thermo-responsive protein treatment for dry eyes [PDF]

open access: yesJournal of Controlled Release, 2015
Millions of Americans suffer from dry eye disease, and there are few effective therapies capable of treating these patients. A decade ago, an abundant protein component of human tears was discovered and named lacritin (Lacrt). Lacrt has prosecretory activity in the lacrimal gland and mitogenic activity at the corneal epithelium.
Wan, Wang   +9 more
openaire   +2 more sources

The Pathogenesis of Staphylococcus aureus Eye Infections

open access: yesPathogens, 2018
Staphylococcus aureus is a major pathogen of the eye able to infect the tear duct, eyelid, conjunctiva, cornea, anterior and posterior chambers, and the vitreous chamber.
R. O'Callaghan
semanticscholar   +1 more source

Human 14-3-3 gamma protein results in abnormal cell proliferation in the developing eye of Drosophila melanogaster

open access: yesCell Division, 2008
Background 14-3-3 proteins are a family of adaptor proteins that participate in a wide variety of cellular processes. Recent evidence indicates that the expression levels of these proteins are elevated in some human tumors providing circumstantial ...
Bosco Giovanni   +4 more
doaj   +1 more source

Functions of retinal astrocytes and Müller cells in mammalian myopia

open access: yesBMC Ophthalmology, 2022
Background Changes in the retina and choroid blood vessels are regularly observed in myopia. However, if the retinal glial cells, which directly contact blood vessels, play a role in mammalian myopia is unknown. We aimed to explore the potential role and
Xuhong Zhang   +10 more
doaj   +1 more source

Ocular mucins in dry eye disease.

open access: yesExperimental Eye Research, 2019
Dry eye disease is a common and multifactorial disease with a high prevalence worldwide. Water loss, reduced expression of glycocalyx mucins, and loss of goblet cells secreting gel-forming mucins are hallmarks of dry eye disease.
Céline Portal   +3 more
semanticscholar   +1 more source

Circadian rhythms in the Drosophila eye may regulate adaptation of vision to light intensity

open access: yesFrontiers in Neuroscience
The sensitivity of the eye at night would lead to complete saturation of the eye during the day. Therefore, the sensitivity of the eye must be down-regulated during the day to maintain visual acuity.
Richard Brent Nolan   +2 more
doaj   +1 more source

Drosophila signal peptidase complex member Spase12 is required for development and cell differentiation. [PDF]

open access: yesPLoS ONE, 2013
It is estimated that half of all proteins expressed in eukaryotic cells are transferred across or into at least one cellular membrane to reach their functional location.
Erin Haase Gilbert   +3 more
doaj   +1 more source

Infantile Central Nervous System Juvenile Xanthogranuloma With Somatic CSF1R Mutation Responsive to Imatinib Monotherapy

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Juvenile xanthogranuloma (JXG) of the central nervous system (CNS) is a rare non‐Langerhans cell histiocytosis. CSF1R mutations have been reported for peripheral JXG, but not in CNS JXG. A 3‐month‐old male presented with fever, lymphadenopathy, and macrocephaly with bulging fontanelles.
Sima Vazquez   +8 more
wiley   +1 more source

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