Results 61 to 70 of about 247,181 (310)

VEGF mRNA and protein concentrations in the developing human eye [PDF]

Pediatric Research, 2015
Vascular endothelial growth factor (VEGF), a well-characterized regulator of angiogenesis, has been mechanistically implicated in retinal neovascularization and in the pathogenesis of retinopathy of prematurity. However, the ontogeny of VEGF expression in the human fetal retina is not well known.
Irene T. Ma, Suzanne McConaghy, Kopperuncholan Namachivayam, Brian A. Halloran, Ashish R. Kurundkar, Krishnan MohanKumar, Akhil Maheshwari, Robin K. Ohls   +7 more
openaire   +2 more sources

Changes of main tear proteins from dry eye patients.

, 2018
Changes of main tear proteins from dry eye patients.
Zhu Huang (455467), Xiao-Dong Pan (444195), Chi-Xin Du (5593520)   +2 more
core   +1 more source

Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration

, 2020
Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is considered to be a key factor in age-related macular degeneration (AMD) pathology.
Uusitalo, Hannu, Sinha, Debasish, Felszeghy, Szabolcs, Kaarniranta, Kai, Salminen, Antero, Ferrington, Deborah, Blasiak, Janusz, Kannan, Ram, Kauppinen, Anu   +8 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Refractive index gradient in the lens: reflections on form and function and on the lens paradox

Frontiers in Ophthalmology
IntroductionThe eye lens is a sophisticated optical element that provides the eye with both refractive power and transparency as well as the ability to change focus.
Barbara K. Pierscionek
doaj   +1 more source

Lacrimal proline rich 4 (LPRR4) protein in the tear fluid is a potential biomarker of dry eye syndrome.

PLoS ONE, 2012
Dry eye syndrome (DES) is a complex, multifactorial, immune-associated disorder of the tear and ocular surface. DES with a high prevalence world over needs identification of potential biomarkers so as to understand not only the disease mechanism but also
Saijyothi Venkata Aluru, Shweta Agarwal, Bhaskar Srinivasan, Geetha Krishnan Iyer, Sivakumar M Rajappa, Utpal Tatu, Prema Padmanabhan, Nirmala Subramanian, Angayarkanni Narayanasamy   +8 more
doaj   +1 more source

Planar polarity in primate cone photoreceptors: a potential role in Stiles Crawford effect phototropism

Communications Biology, 2022
Verschueren et al. expand our understanding of the Stiles-Crawford effect in mammals by using super-high resolution expansion microscopy of the adult macaque eye.
Anna Verschueren, Leyna Boucherit, Ulisse Ferrari, Stéphane Fouquet, Céline Nouvel-Jaillard, Michel Paques, Serge Picaud, José-Alain Sahel   +7 more
doaj   +1 more source

A widespread peroxiredoxin-like domain present in tumor suppression- and progression-implicated proteins. [PDF]

, 2010
Background Peroxide turnover and signalling are involved in many biological phenomena relevant to human diseases. Yet, all the players and mechanisms involved in peroxide perception are not known.
Grynberg Marcin, Marcin Grynberg, Lenart Anna, Anna Muszewska, Szczepińska Teresa, Lenart, Anna, Grynberg, Marcin, Krzysztof Pawłowski, Godzik, Adam, Muszewska Anna, Pawłowski Krzysztof, Muszewska, Anna, Teresa Szczepinska, Pawłowski, Krzysztof, Krzysztof Pawlowski, Godzik Adam, Anna Lenart, Adam Godzik, Szczepińska, Teresa   +18 more
core   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Notes on electropherograms of eye-lens, muscle proteins and zymograms of muscle esterases of fish collected during the first Brazilian expedition to the Antarctica

Brazilian Journal of Oceanography, 1985
A preliminary study was carried out on electropherograms of eye-lens, muscle proteins and zymograms of muscle esterases of ten Notothenia larseni, six Notothenia nudifrons and one lanternfish, Electrona antarctica.
Van Ngan Phan, Hana Suzuki, Vicente Gomes, Maria José de Arruda Campos Rocha Passos   +3 more
doaj   +1 more source