Results 61 to 70 of about 441,178 (207)
The function of tcf3 in medaka embryos: efficient knockdown with pePNAs
BMC Biotechnology, 2018 Background The application of antisense molecules, such as morpholino oligonucleotides, is an efficient method of gene inactivation in vivo. We recently introduced phosphonic ester modified peptide nucleic acids (PNA) for in vivo loss-of-function ...
Gerlinde Doenz +9 more
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Redox Biology, 2023 The retina is one of the highest oxygen-consuming tissues because visual transduction and light signaling processes require large amounts of ATP. Thus, because of the high energy demand, oxygen-rich environment, and tissue transparency, the eye is ...
Sarah C. Stanhope +7 more
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Mutation in the guanine nucleotide-binding protein beta-3 causes retinal degeneration and embryonic mortality in chickens [PDF]
, 2006 PURPOSE. To identify the gene defect that causes blindness and the predisposition to embryonic death in the retinopathy globe enlarged (rge) chicken. METHODS.
Ali, Manir +6 more
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The Eyes Absent Proteins in Developmental and Pathological Angiogenesis [PDF]
The American Journal of Pathology, 2016 Management of neoangiogenesis remains a high-value therapeutic goal. A recently uncovered association between the DNA damage repair pathway and pathological angiogenesis could open previously unexplored possibilities for intervention. An attractive and novel target is the Eyes absent (EYA) tyrosine phosphatase, which plays a critical role in the repair
Yuhua, Wang +6 more
openaire +2 more sources
Drosophila photoreceptors and signaling mechanisms
Frontiers in Cellular Neuroscience, 2009 Fly eyes have been a useful biological system in which fundamental principles of sensory signaling have been elucidated. The physiological optics of the fly compound eye, which was discovered in the Musca, Calliphora and Drosophila flies, has been widely
Ben Katz, Baruch Minke
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Candidate Molecular Compounds as Potential Indicators for Meibomian Gland Dysfunction
Frontiers in Medicine, 2022 Meibomian gland dysfunction (MGD) is the leading cause of dry eye disease throughout the world. Studies have shown that several molecules in meibum, including but not limited to interleukins, amino acids, cadherins, eicosanoids, carbohydrates, and ...
Kofi Asiedu
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Towards Reliable Automatic Protein Structure Alignment
, 2013 A variety of methods have been proposed for structure similarity calculation, which are called structure alignment or superposition. One major shortcoming in current structure alignment algorithms is in their inherent design, which is based on local ...
A. Caprara +31 more
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Refractive index gradient in the lens: reflections on form and function and on the lens paradox
Frontiers in OphthalmologyIntroductionThe eye lens is a sophisticated optical element that provides the eye with both refractive power and transparency as well as the ability to change focus.
Barbara K. Pierscionek
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Antioxidants, 2020 Background: Hyperglycemia-induced oxidative stress plays a key role in diabetic complications, including diabetic retinopathy. The main goal of this study was to assess whether the topical administration (eye drops) of glucagon-like peptide-1 (GLP-1) has
Hugo Ramos +5 more
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Communications Biology, 2022 Verschueren et al. expand our understanding of the Stiles-Crawford effect in mammals by using super-high resolution expansion microscopy of the adult macaque eye.
Anna Verschueren +7 more
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