Localization of complement factor H gene expression and protein distribution in the mouse outer retina. [PDF]
, 2015 To determine the localization of complement factor H (Cfh) mRNA and its protein in the mouse outer retina.Quantitative real-time PCR (qPCR) was used to determine the expression of Cfh and Cfh-related (Cfhr) transcripts in the RPE/choroid.
Estep, Jason +6 more
core +1 more source
Cornea organoids from human induced pluripotent stem cells. [PDF]
, 2017 The cornea is the transparent outermost surface of the eye, consisting of a stratified epithelium, a collagenous stroma and an innermost single-cell layered endothelium and providing 2/3 of the refractive power of the eye. Multiple diseases of the cornea
Adams, Sheila M +5 more
core +3 more sources
Calcium channel-dependent molecular maturation of photoreceptor synapses. [PDF]
PLoS ONE, 2013 Several studies have shown the importance of calcium channels in the development and/or maturation of synapses. The Ca(V)1.4(α(1F)) knockout mouse is a unique model to study the role of calcium channels in photoreceptor synapse formation.
Nawal Zabouri, Silke Haverkamp
doaj +1 more source
Too sweet: Problems of protein glycation in the eye
Experimental Eye Research, 2019 Laboratory and epidemiological data indicate that high blood sugar levels and/or consuming high glycemia diets are linked to multiple age-related diseases, including age-related macular degeneration, cataract, Parkinson's disease, Alzheimer's disease, diabetic retinopathy, and, apparently glaucoma.
Eloy Bejarano, Allen Taylor
openaire +3 more sources
An Eye on Trafficking Genes: Identification of Four Eye Color Mutations in Drosophila
G3: Genes, Genomes, Genetics, 2016 Genes that code for proteins involved in organelle biogenesis and intracellular trafficking produce products that are critical in normal cell function . Conserved orthologs of these are present in most or all eukaryotes, including Drosophila melanogaster.
Paaqua Grant +7 more
doaj +1 more source
RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry [PDF]
, 2018 Ciliopathies are a group of genetically heterogeneous disorders, characterized by defects in cilia genesis or maintenance. Mutations in the RPGR gene and its interacting partners, RPGRIP1 and RPGRIP1L, cause ciliopathies, but the function of their ...
Aguirre +68 more
core +3 more sources
Proteomic Study of Retinal Proteins Associated with Transcorneal Electric Stimulation in Rats
Journal of Ophthalmology, 2015 Background. To investigate how transcorneal electric stimulation (TES) affects the retina, by identifying those proteins up- and downregulated by transcorneal electric stimulation (TES) in the retina of rats. Methods.
Takashi Kanamoto +6 more
doaj +1 more source
HPLC analysis of closed, open, and reflex eye tear proteins
Indian Journal of Ophthalmology, 1998 Changes in the closed, open and reflex eye tear proteins of normal subjects were compared and analysed. Tear proteins were resolved by high-performance liquid chromatography (HPLC) utilising both gel filtration (P-300 SW) and reverse-phase (C-18) columns
Sitaramamma T, Shivaji S, Rao Gullapalli
doaj
Seroepidemiological studies of herpesvirus-associated diseases of marine turtles: Fibropapillomatosis and lung-eye-trachea disease [PDF]
, 2001 We have developed immunological tests that can identify marine turtles in Florida (green and loggerhead) that have been exposed to the LETV herpesvirus.
Jacobson, Elliott, Klein, Paul A.
core
A Fiber Optic Probe for the Detection of Cataracts [PDF]
, 1993 A compact fiber optic probe developed for on-orbit science experiments was used to detect the onset of cataracts, a capability that could eliminate physicians' guesswork and result in new drugs to 'dissolve' or slow down the cataract formation before ...
Ansari, Rafat R., Dhadwal, Harbans S.
core +1 more source