Results 91 to 100 of about 247,181 (310)
Accumulation of protein- and lipid-containing deposits external to the retinal pigment epithelium (RPE) is common in the aging eye, and has long been viewed as the hallmark of age-related macular degeneration (AMD).
Flinn, JM +14 more
core
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
Biophysical characteristics of human milk proteins for enhancing tear stability in dry eye [PDF]
Purpose : Dry eye disease affects millions of people worldwide and is prevalent in older people, females, contact lens wearers, and increasingly in the general population due to excessive use of visual display devices.
Pedler, Michelle +3 more
core
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
Electrophoretic characteristics of oil sardine (Sardinella longiceps) and mackerel (Rastrelliger kanagurta) eye lens proteins [PDF]
Electrophoresis of eye lens proteins of oil sardine and mackerel showed separation of proteins into three and four components, indicating the heterogeneous nature of the ...
Narasimha Rao, S., Dhulkhed, M.H.
core +1 more source
Proteomic interrogation of human chromatin. [PDF]
Chromatin proteins provide a scaffold for DNA packaging and a basis for epigenetic regulation and genomic maintenance. Despite understanding its functional roles, mapping the chromatin proteome (i.e. the "Chromatome") is still a continuing process. Here,
LeRoy, Gary +22 more
core +1 more source
Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions
ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos +5 more
wiley +1 more source
Cronobacter sakazakii is an opportunistic foodborne pathogen and the virulence differences were previously documented. However, information about membranous proteins involved in virulence differences was not available.
Yingwang eYe
core +1 more source
Proteomic Study of Retinal Proteins Associated with Transcorneal Electric Stimulation in Rats
Background. To investigate how transcorneal electric stimulation (TES) affects the retina, by identifying those proteins up- and downregulated by transcorneal electric stimulation (TES) in the retina of rats. Methods.
Takashi Kanamoto +6 more
doaj +1 more source
The Bi-Functional Organization of Human Basement Membranes [PDF]
The current basement membrane (BM) model proposes a single-layered extracellular matrix (ECM) sheet that is predominantly composed of laminins, collagen IVs and proteoglycans.
Paul Bernhard Henrich (430036) +40 more
core +1 more source

