Retinal S-antigen Th1 cell epitope mapping in patients with Behcet's disease [PDF]
Background - Retinal S-antigen (S-Ag) is a most characterized autoantigen of autoimmune uveitis. The recognized immunodominant epitope of human S-Ag in patients with uveitis has not been identified. In this study, we selected certain patients with active
Du, L.P. +6 more
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Oral administration of antigen in the treatment of eye disease [PDF]
, 1997 Comment on the Oral administration of antigen in the treatment of eye ...
Williams, Keryn Anne
core +1 more source
Nanotherapy for Neural Retinal Regeneration
Advanced Science, Volume 12, Issue 24, June 26, 2025.Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu +11 more
wiley +1 more source
Involvement of Angiopoietin 2 and vascular endothelial growth factor in uveitis.
PLoS ONE, 2023 PurposeAngiopoietin (Ang) 2 is released from vascular endothelial cells by the stimulation of vascular endothelial growth factor (VEGF)A. Ang2 increases the expression of leukocyte adhesion molecules on endothelial cells via nuclear factor κB. The aim of
Kayo Suzuki +8 more
doaj +1 more source
Environmental conditioning in the control of macrophage thrombospondin-1 production [PDF]
, 2012 Thrombospondin-1 (TSP-1) is a multifunctional protein which is secreted into the extracellular matrix during inflammation, where it modulates numerous components of the immune infiltrate.
Copland, David A. +6 more
core +1 more source
Understanding exosomes: Part 2—Emerging leaders in regenerative medicine
Periodontology 2000, Volume 94, Issue 1, Page 257-414, February 2024.Abstract Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells with the ability to communicate with other tissues and cell types over long distances. Their use in regenerative medicine has gained tremendous momentum recently due to their ability to be utilized as therapeutic options for a wide array of diseases ...
Richard J. Miron +3 more
wiley +1 more source
Ropivacaine vs tetracaine in topical anesthesia for intravitreal injection [PDF]
, 2015 Aim: The object of the study was to evaluate the long term efficacy and safety of ropivacaine 0,5% vs tetracaine 0,5% for topical anesthesia in intravitreal injection of dexamethasone in patients with diabetic macular edema (DME) and anti-vascular ...
COLLINI, Saul +6 more
core +1 more source
CC chemokine receptor 5 polymorphism in Italian patients with Behcet's disease. [PDF]
, 2012 Objective. To evaluate the potential role of CC chemokine receptor 5 (CCR5)Δ32 polymorphism in the susceptibility to and clinical expression of Behçet's disease (BD) in a cohort of Italian patients.Methods.
Atzeni, F +14 more
core +2 more sources
IL-10 has a protective role in experimental autoimmune uveoretinitis [PDF]
International Immunology, 1998 The role of IL-10 in the regulation of ocular autoimmune disease was studied in experimental autoimmune uveoretinitis (EAU) elicited in mice by immunization with the retinal antigen interphotoreceptor retinoid binding protein. IL-10-deficient mice were susceptible to EAU, indicating that pathogenesis can occur without presence of IL-10.
L V, Rizzo +4 more
openaire +2 more sources
One year study of efficacy and safety of infliximab in the treatment of patients with ocular and neurological Behçet's disease refractory to standard immunosuppressive drugs [PDF]
, 2011 The aim of the study was to assess the long-term efficacy and safety of Infliximab therapy in the treatment of patients with Behçet’s disease refractory to standard immunosuppressive agents. Twenty-one patients that did not respond to corticosteroids and
CICCIA, Francesco +5 more
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