Results 91 to 100 of about 23,725,775 (352)
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Artifact, 2014 Commonly the term “experiment” is in the first place associated with science, systematic methods and strict principles for the sake of knowledge creation. Nonetheless, the term is widely used across the boundaries of science.
Steffen, Dagmar
doaj +3 more sources
Experimental design and quantitative analysis of microbial community multiomics
Genome Biology, 2017 Studies of the microbiome have become increasingly sophisticated, and multiple sequence-based, molecular methods as well as culture-based methods exist for population-scale microbiome profiles. To link the resulting host and microbial data types to human
Himel Mallick +5 more
semanticscholar +1 more source
Teaching Experimental Design [PDF]
ILAR Journal, 2014 Awareness of poor design and published concerns over study quality stimulated the development of courses on experimental design intended to improve matters. This article describes some of the thinking behind these courses and how the topics can be presented in a variety of formats.
openaire +3 more sources
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
General Statistical Design of an Experimental Problem for Harmonics [PDF]
, 2004 Four years ago, the Michelin Tire Corporation proposed a problem on experimental design, to improve the manufacturing process for their tires. The idea is basically to determine the effects of placements for various layers built up in the construction of
Lamoureux, Michael
core
Methods in Psychology, 2021 Social group memberships are primarily studied in quasi-experimental contexts, but how can culture, class and gender be manipulated in true experimental designs?
Christine Ma-Kellams
doaj
Biostatistics & Epidemiology, 2018 Quasi-experiments are similar to randomized controlled trials in many respects, but there are many challenges in designing and conducting a quasi-experiment when internal validity threats are introduced from the absence of randomization.
M. Maciejewski
semanticscholar +1 more source
, 2020 This entry introduces the principles of experimental designs, the role played by randomisation in establishing causal inference, and thus the importance of these designs in establishing what works in policy and practice. It explains how randomisation helps to eliminate alternate explanations for any relationship established between an intervention ...
openaire +3 more sources
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source