Results 51 to 60 of about 2,979,229 (315)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Elements of the synthesis method for the layout of a front-line aircraft [PDF]

E3S Web of Conferences, 2019
The article describes a technique that allows to form a planned projection of the aircraft using the minimum number of iterations (refinements based on aerodynamic and weight calculations results).
Dolgov Oleg, Bibikov Sergey, Pocebneva Irina   +2 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Consistency of Yield Ranking and Adaptability Patterns of Winter Wheat Cultivars between Multi-Environmental Trials and Farmer Surveys

Agronomy, 2019
Cultivar recommendation based on mean performance determined by multi-environment trials (METs) conducted on research stations could be unreliable and ineffective for assessing performance in farmers’ fields.
Marcin Studnicki, Manjit S. Kang, Marzena Iwańska, Tadeusz Oleksiak, Elżbieta Wójcik-Gront, Wiesław Mądry   +5 more
doaj   +1 more source

Mechanical behavior of a titanium alloy scaffold mimicking trabecular structure

Journal of Orthopaedic Surgery and Research, 2020
Background Additively manufactured porous metallic structures have recently received great attention for bone implant applications. The morphological characteristics and mechanical behavior of 3D printed titanium alloy trabecular structure will affect ...
Chunqiu Zhang, Lan Zhang, Lu Liu, Linwei Lv, Lilan Gao, Nian Liu, Xin Wang, Jinduo Ye   +7 more
doaj   +1 more source

Optimal plot size for experimentation of common beans (Phaseolus vulgaris L.) in the northern region of Minas Gerais, Brazil

Revista de la Facultad de Ciencias Agrarias, 2021
The objective was to evaluate the minimum size of experimental plots for the common bean (Phaseolus vulgaris L.) using the modified maximum curvature method. The experiment consisted of a uniformity trial with the cultivar BRSFC-402 sown at a spacing
Bruno Vinícius Castro Guimarães, Abner José de Carvalho, Ignacio Aspiazú, Liliane Santana da Silva, Rafael Rogério Pereira da Silva, Amanda Maria Leal Pimenta, Marielly Maria Almeida Moura   +6 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Modeling the early stages of a user-centered process in architectural design through adaptation of the methodologies of New Product Design [PDF]

, 2009
In order to reach a degree of quality in architectural buildings that is likely to lead to user satisfaction, architectural design relies on integrating user-related information even before generation of building concepts.
BOUCHARD, Carole, SONG, Heon, DUCHAMP, Robert   +2 more
core  

Integration of the Experience-Based Approaches with the Early Phase Architectural Design Studios

Megaron, 2017
As architectural design studios are the places where designing is learnt through experimenting designs, it forms the basic framework of the education of architecture.
Ömür Kararmaz, Ayşen Ciravoğlu
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source