Results 61 to 70 of about 23,725,775 (352)

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

open access: yesFEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta   +3 more
wiley   +1 more source

Experimental Design Modulates Variance in BOLD Activation: The Variance Design General Linear Model

open access: yes, 2018
Typical fMRI studies have focused on either the mean trend in the blood-oxygen-level-dependent (BOLD) time course or functional connectivity (FC). However, other statistics of the neuroimaging data may contain important information.
Gaut, Garren   +3 more
core   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Elements of the synthesis method for the layout of a front-line aircraft [PDF]

open access: yesE3S Web of Conferences, 2019
The article describes a technique that allows to form a planned projection of the aircraft using the minimum number of iterations (refinements based on aerodynamic and weight calculations results).
Dolgov Oleg   +2 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Introduction to fMRI: experimental design and data analysis [PDF]

open access: yes, 2008
This provides an introduction to functional MRI, experimental design and data analysis procedures using statistical parametric mapping ...
Miyapuram, Krishna P.
core  

Experimental Design of a Prescribed Burn Instrumentation

open access: yes, 2018
Observational data collected during experiments, such as the planned Fire and Smoke Model Evaluation Experiment (FASMEE), are critical for progressing and transitioning coupled fire-atmosphere models like WRF-SFIRE and WRF-SFIRE-CHEM into operational use.
Fournier, Aimé   +2 more
core   +1 more source

Feasibility Study Design And Laboratory Management Of Experimental Animals In Poltekkes Kemenkes Semarang

open access: yesLINK, 2015
Laboratory is the main supporting to reach the learning aim that appropriate competency for Nutrition Department students. Utilization of experimental animals as objects experiment in the laboratory to test in vivo ( laboratory with experimental animals )
S.Y Didik Widianto   +2 more
doaj   +1 more source

Wood-Veneer-Reinforced Mycelium Composites for Sustainable Building Components

open access: yesBiomimetics, 2022
The demand for building materials has been constantly increasing, which leads to excessive energy consumption for their provision. The looming environmental consequences have triggered the search for sustainable alternatives.
Eda Özdemir   +10 more
doaj   +1 more source

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