Results 111 to 120 of about 4,723,194 (346)

Removal of fluoride from aqueous solution by adsorption on hydroxyapatite (HAp) using response surface methodology

Journal of Saudi Chemical Society, 2015
A study on the adsorption of fluoride onto hydroxyapatite was conducted and the process parameters were optimized using Response Surface Methodology (RSM). Hydroxyapatite has been characterized by using different physicochemical methods.
M. Mourabet, A. El Rhilassi, H. El Boujaady, M. Bennani-Ziatni, R. El Hamri, A. Taitai   +5 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Display/control requirements for automated VTOL aircraft [PDF]

A systematic design methodology for pilot displays in advanced commercial VTOL aircraft was developed and refined. The analyst is provided with a step-by-step procedure for conducting conceptual display/control configurations evaluations for simultaneous
Hoffman, W. C., Kleinman, D. L., Young, L. R.   +2 more
core   +1 more source

Algorithm Engineering in Robust Optimization

, 2015
Robust optimization is a young and emerging field of research having received a considerable increase of interest over the last decade. In this paper, we argue that the the algorithm engineering methodology fits very well to the field of robust ...
A Agra, A Atamtürk, A Beck, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Ben-Tal, A Erera, A Kasperski, A Kasperski, A Kasperski, A Kasperski, A Mutapcic, A Ouorou, A Sbihi, A Schöbel, A Soyster, A Takeda, AB Chassein, B Roy, C Bohle, C Büsing, C Büsing, C Liebchen, D Bertsimas, D Bertsimas, D Bertsimas, D Bertsimas, D Bertsimas, D Bertsimas, D Bertsimas, D Bertsimas, D Catanzaro, D Delling, D Golovin, DJ Alem, DJ Thuente, E Conde, E Conde, E Conde, E Conde, F Bruns, F Pérez-Galarce, F Taniguchi, G Calafiore, G Calafiore, GC Calafiore, H Aissi, H Aissi, H Iida, H Mausser, H Yaman, HE Mausser, I Averbakh, I Averbakh, J Goh, J Lin, J Löfberg, J Pereira, J Xu, JE Falk, JLG Velarde, JM Mulvey, JR Farias de, KS Goetzmann, L Jenkins, LE Ghaoui, M Bürger, M Fischetti, M Fischetti, M Fischetti, M Goerigk, M Goerigk, M Goerigk, M Goerigk, M Goerigk, M Goerigk, M Goerigk, M Goerigk, M Goerigk, M Inuiguchi, M López, M Monaci, M Monaci, MC Campi, MK Zanjani, N Eggenberg, O Berman, P Adasme, P Kouvelis, P Sanders, P Zieliński, PC Bouman, R Kalai, R Khandekar, R Montemanni, R Montemanni, R Montemanni, R Reemtsen, S Cicerone, S Siddiqui, S Suzuki, TS Ng, U Feige, V Cacchiani, V Jeyakumar, X Song, Y Nikulin, Y Yin   +114 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

RESPONSE SURFACE METHODOLOGY APPLIED TO LACCASES ACTIVITIES EXHIBITED BY STENOTROPHOMONAS MALTOPHILIA AAP56 IN DIFFERENT GROWTH CONDITIONS

BioResources, 2011
Stenotrophomonas maltophilia AAP56, laccase-producing bacteria, growing under different conditions, exhibit laccase activity that is highly affected by some environmental factors.
Said Galai,, Youssef Touhami,, Med Nejib Marzouki   +2 more
doaj  

Response Surface Methodology in Biodiesel Production and Engine Performance Assessment

International Journal of Thermofluids
Biodiesel is a sustainable and green fuel with high potential for mitigating the adverse environmental impacts associated with conventional fossil fuels.
Sara Maen Asaad, Abrar Inayat, Chaouki Ghenai, Abdallah Shanableh   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source