Oxidative stress, protein glycation and nutrition – interactions relevant to health and disease throughout the lifecycle [PDF]
Protein glycation has been studied for over a century now and plays an important role in disease pathogenesis throughout the lifecycle. Strongly related to diabetic complications, glycation of Hb has become the gold standard method for diabetes diagnosis
American Diabetes +17 more
core +3 more sources
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu +10 more
wiley +1 more source
Introduction: Based on the routine surveillance of non-communicable diseases (NCDs) hospital based in South Sulawesi diabetes mellitus highest cause of death in the amount of 41.56%.
Hasnah Hasnah, Ambo Sau
doaj +1 more source
The Influence of Diabetic Foot Gymnastic to Body Balance in Elderly Diabetes Mellitus Patients in Gatoel Mojokerto Hospital Diabetic Club [PDF]
Diabetes mellitus suffers from insulin deficiency which inhibited the transfer of glucose to cells in body tissues that cause starvation cells an in the increase in glucose in the blood that leads to muscle weakness thus disrupt the body’s balance and ...
Muhith, A. M. (Abdul) +5 more
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Upregulation of inducible NO synthase by exogenous adenosine in vascular smooth muscle cells activated by inflammatory stimuli in experimental diabetes [PDF]
BACKGROUND: Adenosine has been shown to induce nitric oxide (NO) production via inducible NO synthase (iNOS) activation in vascular smooth muscle cells (VSMCs). Although this is interpreted as a beneficial vasodilating pathway in vaso-occlusive disorders,
Cignarella, Andrea +4 more
core +2 more sources
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Remodeling of adipose tissue at experimental diabetes mellitus
Introduction Diabetes mellitus (DM) type 1 is chronіc disease whith progressive selective destruction of β- cells pancreatic islets (of Langerhans) and whith development of absolute insulin failure.
O. A. Konovalova, A. M. Kamyshnyi
doaj +1 more source
β-Cell Autophagy Pathway and Endoplasmic Reticulum Stress Regulating-Role of Liposomal Curcumin in Experimental Diabetes Mellitus: A Molecular and Morphometric Study. [PDF]
Khater SI +11 more
europepmc +1 more source
Effectiveness of dietary intervention among people with diabetes mellitus: A quasi-experimental study [PDF]
Sanjeev Gupta +4 more
openalex +1 more source
The comparison of hearing loss among diabetic and non-diabetic patients [PDF]
Introduction: The prevalence of Diabetes Mellitus is steadily increasing. This is a multi- systemic abnormality, causing side- effects which are mainly irreversible.
Mansourian Azad, R., Taziki Mohammad, H.
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