Results 111 to 120 of about 641,645 (355)

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

The latest progression of N6-methyladenosine (m6A) RNA modification in diabetes mellitus and diabetic complications

Frontiers in Endocrinology
The increasing global prevalence of diabetes mellitus and its complications continues to encourage exploration of novel molecular mechanisms for their prevention and treatment.
Guangyang Yin, Jiajing Hong, Guohui Shan, Cuizhu Xu, Bailin Li, Dongyu Yang   +5 more
doaj   +1 more source

Streptozotocin model of stable diabetes mellitus

Вестник трансплантологии и искусственных органов, 2019
Aim: to create a model of stable experimental diabetes mellitus (DM) in laboratory rats using streptozotocin (STZ).Materials and methods. The dynamics of changes in glycemia and survival in 60 Wistar rats was determined.
G. N. Skaletskaya, N. N. Skaletskiy, E. A. Volkova, V. I. Sevastyanov   +3 more
doaj   +1 more source

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

Advanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang, Haowei Fang, Lili Qi, Song Myoungseop, Aawrish Khan, Lunli Gong, Guangdong Zhou, Kunxi Zhang, Haiyan Cui   +8 more
wiley   +1 more source

Application of precise nutrition management in patients with gestational diabetes mellitus

Huli yanjiu, 2017
Objective:To probe into the application effect of precise nutrition management for patients with gestational diabetes mellitus.Methods: A total of 200 cases of patients with gestational diabetes mellitus were divided into experimental group with 96 ...
刘君, 蒋盘华, 付锦艳, 朱庆贤
doaj  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

ANALISIS EFEKTIVITAS BIAYA TERAPI KOMBINASI ANTIHIPERTENSI PADA PASIEN HIPERTENSI KOMPLIKASI DIABETES MELLITUS TIPE 2 PASIEN RAWAT INAP DI RSI AISYIYAH KOTA MALANG [PDF]

Background: Hypertension and diabetes mellitus are interrelated diseases that affect an individual to be atherosclerotic disease. Hypertension is also associated with 30% mortality in patients with diabetes mellitus.
Rusyidah, Fakhriyah Iklil
core  

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes. [PDF]

, 1996
We previously demonstrated that a spontaneous Th1 response against glutamate decarboxylase (GAD65) arises in NOD mice at four weeks in age and subsequently T cell autoimmunity spreads both intramolecularly and intermolecularly.
Atkinson, MA, Clare-Salzler, M, Forsthuber, T, Herschenfeld, A, Kaufman, DL, Lehmann, PV, Tian, J   +6 more
core  

THE USE OF CERTAIN SULFONAMIDES IN THE TREATMENT OF EXPERIMENTAL DIABETES MELLITUS [PDF]

, 1956
A Loubatières
openalex   +1 more source