Results 101 to 110 of about 7,303,354 (262)

Effect of extracts of Geranium ayavacense W. (Pasuchaca) on glycemia on rats with experimental diabetes mellitus

open access: yesRevista Peruana de Medicina Experimental y Salud Pública, 2014
Objectives. To determine if the lyophilized aqueous extract of Geranium ayavacense (Pasuchaca) has any effect on glycemia in rats with experimental diabetes mellitus. Materials and methods. Experimental diabetes was induced with alloxan. Rats included in
José Aranda-Ventura   +3 more
doaj   +1 more source

Nephroprotective Effect of the Virgin Olive Oil Polyphenol Hydroxytyrosol in Type 1-like Experimental Diabetes Mellitus: Relationships with Its Antioxidant Effect. [PDF]

open access: yesAntioxidants (Basel), 2021
Rodríguez-Pérez MD   +8 more
europepmc   +1 more source

Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin [PDF]

open access: yes, 2010
OBJECTIVE The aim of this study was to investigate whether apolipoprotein B100 of LDL suffers increased damage by glycation, oxidation, and nitration in patients with type 2 diabetes, including patients receiving metformin therapy.
Rabbani, Naila   +11 more
core   +1 more source

Multifunctional Manganese Oxide Nanocomposite Hydrogel With Synergistic Reactive Oxygen Species‐Scavenging, Oxygen‐Generating, Immunomodulatory, and Photothermal Antimicrobial Activities for Enhanced Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
CFP/PC@MnO2 hydrogel integrates ROS scavenging, oxygen delivery, oxidative stress reduction, immunomodulation, and photothermal antibacterial properties. The incorporation of PC@MnO2 NPs endows the hydrogel with multiple functional advantages tailored to the pathological microenvironment of diabetic wounds, including efficient ROS clearance, mitigation
Zhi Xu   +9 more
wiley   +1 more source

Streptozotocin model of stable diabetes mellitus

open access: yesВестник трансплантологии и искусственных органов, 2019
Aim: to create a model of stable experimental diabetes mellitus (DM) in laboratory rats using streptozotocin (STZ).Materials and methods. The dynamics of changes in glycemia and survival in 60 Wistar rats was determined.
G. N. Skaletskaya   +3 more
doaj   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li   +8 more
wiley   +1 more source

Effect of induced gestational diabetes on TBX20 gene expression in the heart of the 11.5-day-old embryo of the C57BL/6 mouse

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2021
Background and Objective: Diabetes mellitus is one of the most common metabolic and global health threats. The gene needed for the development of the TBX20 gene is the fusion of the gene, and the defect in the sequence and expression of this gene also ...
Zeynab Alinezhad   +2 more
doaj  

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen   +7 more
wiley   +1 more source

Application of precise nutrition management in patients with gestational diabetes mellitus

open access: yesHuli yanjiu, 2017
Objective:To probe into the application effect of precise nutrition management for patients with gestational diabetes mellitus.Methods: A total of 200 cases of patients with gestational diabetes mellitus were divided into experimental group with 96 ...
刘君, 蒋盘华, 付锦艳, 朱庆贤
doaj  

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

open access: yesAdvanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang   +18 more
wiley   +1 more source

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