Results 121 to 130 of about 641,645 (355)

Versatile DNA Hydrogel‐Mediated Delivery of Ginsenoside‐Encapsulated Small Extracellular Vesicles to Boost Diabetic Wound Repair

Advanced Science, EarlyView.
This study presents a DNA hydrogel‐mediated delivery system, in which ginsenoside (GS) molecules are incorporated into small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSCs) and the formed complexes are then anchored in DNA hydrogels via aptamer‐CD63 affinity as “GS/sEV@DNAgels”, to improve diabetic wound repair.
Jianming Xing, Shuangyang Li, Yuning Wang, Xushuang Jia, Ruiting Lin, Xintong Liu, Dongxu Wang, Ning Cui, Peng Ji, Jiaqi Chen, Shengnian Wang, Guangzhe Li, Ye Teng, Da Liu, Ye Jin   +14 more
wiley   +1 more source

Stages of development of streptozotocin-induced experimental diabetes mellitus

Journal of Education, Health and Sport, 2017
The article presents data about the stages of experimental diabetes mellitus under conditions of the streptozotocin administration. It is noted that in the early development of experimental diabetes, changes in the kidneys proceeds in three stages ...
T. M. Boychuk, M. I. Grytsiuk, A. I. Gozhenko   +2 more
doaj   +1 more source

The Role of Physical Activity in the Primary Prevention of Type 2 Diabetes via the Amelioration of Insulin Resistance. [PDF]

, 2010
Type 2 diabetes is the most common endocrine disease in our society, affecting around 5% of Western populations, whilst showing a steady rise in prevalence. The complications that arise from the disease are known to cause morbidity and mortality, and are
Routen, Ashley
core   +1 more source

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

Effectiveness of dietary intervention among people with diabetes mellitus: A quasi-experimental study [PDF]

, 2023
Sanjeev Gupta, P. V. M. Lakshmi, Sumit Malhotra, Ashu Rastogi, M Kaur   +4 more
openalex   +1 more source

From Cell‐Free Transcriptomes to Single‐Cell Landscapes: Biomarker Discovery and Originating Cell Alteration Analysis via Graph Matrix Factorization

Advanced Science, EarlyView.
CellFreeGMF traces plasma cfRNA to likely originating cell types by integrating single‐cell atlases with graph‐regularized matrix factorization. The method decomposes cfRNA profiles into sample–cell contributions to reconstruct pseudo single‐cell expression.
Wenxiang Zhang, Wenjing Zhang, Hang Wei, Shiyan Liu, Junliang Shang, Weijie Gong, Hanwen Cheng, Xiujuan Lei, Yuhui Kou, Baoguo Jiang   +9 more
wiley   +1 more source

Bright Renoprotective Properties of Metformin Beyond Blood Glucose Regulatory Effects [PDF]

, 2013
Metformin, a biguanide drug, is widely prescribed to treat high blood glucose in individuals with type 2 diabetes mellitus. Type 2 diabetes mellitus is a troubling chronic disease and diabetic nephropathy is one of the most important complications of ...
Ardalan, Mohammadreza., Baradaran, Azar., Mardani, Saeed., Momeni, Ali., Nasri, Hamid., Rafieian-Kopaei, Mahmoud.   +5 more
core  

Large‐Scale Quantitative Morphometry of Platelet α‐Granules via SIM Super‐Resolution Microscopy for Cancer Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma, Huan Deng, Zelin Liu, Simei Zhong, Liangliang Wang, Mu He, Ning Jing, Lihua Dai, Yuzhen Basang, Xiao‐Yu Hu, Changyi Zhang, Huimin Zeng, Haoren Shao, Zhe Yang, Shanshan Zhao, Xiaohai Hu, Chuanjie Zhang, Xiaowei Wu, Jing Xu, Shaoqun Zeng, Jing Yuan, Qiang Li, Ziwei Qu, Zhenya Hong, Lingjuan Chen, Hanhua Dong, Jia Guo, Zhiqiang Han, Yu‐Hui Zhang   +28 more
wiley   +1 more source

Comparative study of the neuroprotective activity of lithium compounds and their effect on the course of experimental alloxan diabetes mellitus in rats

, 2021
O. A. Nazarenko, В. И. Демидов, О. А. Громова, Е. Л. Алексахина, I. Yu. Torshin   +4 more
openalex   +2 more sources

Reply to the Comments on “GLM7—A Novel Composite Glycolipid Index Derived from Routine Health Indicators for Enhanced Diagnosis and Prediction of Multimorbidity”

Advanced Science, EarlyView.
ABSTRACT This paper is a formal response to the comments raised by Yiquan Wang et al. and Peikai Sun et al. on our published work entitled “GLM7–A Novel Composite Glycolipid Index Derived from Routine Health Indicators for Enhanced Diagnosis and Prediction of Multimorbidity”. We address all the comments in this response.
Zhihua Wang, Suowen Xu
wiley   +1 more source