Results 111 to 120 of about 751,176 (305)

Situating Language in the Real-World: Authors’ Reply to Commentaries

open access: yesJournal of Cognition, 2021
Margherita Murgiano   +2 more
doaj   +1 more source

Evolution after gene duplication : Models, mechanisms, sequences, systems, and organisms [PDF]

open access: yes, 2007
Gene duplication is postulated to have played a major role in the evolution of biological novelty. Here, gene duplication is examined across levels of biological organization in an attempt to create a unified picture of the mechanistic process by which ...
Rastogi, Shruti   +6 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Beyond EICA : understanding post-establishment evolution requires a broader evaluation of potential selection pressures [PDF]

open access: yes, 2011
Research on post-establishment evolution in nonnative plant populations has focused almost exclusively on testing the Evolution of Increased Competitive Ability (EICA) hypothesis, which posits that the lack of specialized herbivores in the invaded range ...
Laura Meyerson   +8 more
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Experimental Evolution with Caenorhabditis Nematodes [PDF]

open access: yes, 2017
The hermaphroditic nematode Caenorhabditis elegans has been one of the primary model systems in biology since the 1970s, but only within the last two decades has this nematode also become a useful model for experimental evolution.
Estes, Suzanne   +7 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Dynamics of Dark-Fly Genome Under Environmental Selections

open access: yesG3: Genes, Genomes, Genetics, 2016
Environmental adaptation is one of the most fundamental features of organisms. Modern genome science has identified some genes associated with adaptive traits of organisms, and has provided insights into environmental adaptation and evolution.
Minako Izutsu   +4 more
doaj   +1 more source

Experimental evolution of slowed cognitive aging in Drosophila melanogaster [PDF]

open access: yes, 2017
Reproductive output and cognitive performance decline in parallel during aging, but it is unknown whether this reflects a shared genetic architecture or merely the declining force of natural selection acting independently on both traits.
Kawecki, Tadeusz J.   +7 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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