Genetic and virulence factors behind the success of high-risk <i>Pseudomonas aeruginosa</i> clones: insights from comparative genomics and an experimental infection model. [PDF]
de Sales RO +8 more
europepmc +1 more source
ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Alexia Moukhine +40 more
wiley +1 more source
Experimental infection of purebred Saanen goats high pathogenicity and virulence of Babesia aktasi. [PDF]
Ulucesme MC, Ozubek S, Aktas M.
europepmc +1 more source
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
Experimental infection of shrews (<i>Crocidura russula</i>) with Borna disease virus 1: Insights into viral spread and shedding. [PDF]
Nobach D +5 more
europepmc +1 more source
Endothelial Cell Proteins as Biomarkers in Susac Syndrome
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin +11 more
wiley +1 more source
Schmallenberg virus non-structural proteins NSs and NSm are not essential for experimental infection of <i>Culicoides sonorensis</i> biting midges. [PDF]
Wernike K +8 more
europepmc +1 more source
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou +6 more
wiley +1 more source
Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui +10 more
wiley +1 more source
Sheep Displayed No Clinical and Parasitological Signs upon Experimental Infection with Babesia aktasi. [PDF]
Ulucesme MC, Ozubek S, Aktas M.
europepmc +1 more source

