Results 71 to 80 of about 934,796 (284)
, 2004 We re-examine Peres' statement ``opposite momenta lead to opposite directions''. It will be shown that Peres' statement is only valid in the large distance or large time limit.
De Baere, W. +3 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Fracture mechanics of plate debonding: experimental validation
, 2009 Premature plate debonding hampers the efficient use of externally bonded FRP plates for flexural strengthening of concrete beams. Existing research mostly concentrates on finite element (FE) modelling of the concrete–FRP interface but such analyses are ...
Achintha, M., Burgoyne, C.
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Influence of additional static stresses on biaxial low-cycle fatigue of 2024 aluminum alloy
Fracture and Structural Integrity, 2022 In this paper, a previously developed modification of the Sainz model of multiaxial fatigue is reduced to an invariant form. Model constants were determined for different sets of setup experiments.
Andrey Yankin +4 more
doaj +2 more sources
Fracture and Structural Integrity, 2020 Axial alternating fatigue tests with superimposed static torsional mean stress and shear alternating fatigue tests with superimposed static tensile mean stress are represented.
Andrey Yankin +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Measuring strain in sheet metals [PDF]
FME Transactions, 2019 A sensitive and precise experimental system able to time-track the static and dynamic response of steel sheets to intense loads is hereby described.
Braut Sanjin +3 more
doaj
Physical concepts in the development of constitutive equations [PDF]
Proposed viscoplastic material models include in their formulation observed material response but do not generally incorporate principles from thermodynamics, statistical mechanics, and quantum mechanics.
Cassenti, B. N.
core +1 more source