Results 71 to 80 of about 1,456,951 (295)

SPREAD: a high-resolution daily gridded precipitation dataset for Spain – an extreme events frequency and intensity overview [PDF]

Earth System Science Data, 2017
A high-resolution daily gridded precipitation dataset was built from raw data of 12 858 observatories covering a period from 1950 to 2012 in peninsular Spain and 1971 to 2012 in Balearic and Canary islands.
R. Serrano-Notivoli, R. Serrano-Notivoli, R. Serrano-Notivoli, S. Beguería, M. Á. Saz, M. Á. Saz, L. A. Longares, L. A. Longares, M. de Luis, M. de Luis   +9 more
doaj   +1 more source

A Critical Look at the Abstraction Based on Macro-Operators [PDF]

, 2004
ion can be an effective technique for dealing with the complexity of planning tasks. This paper is aimed at assessing and identifying in which cases abstraction can actually speed-up the overall search.
ARMANO G, CHERCHI G, VARGIU E
core  

Probabilistic Hybrid Action Models for Predicting Concurrent Percept-driven Robot Behavior

, 2005
This article develops Probabilistic Hybrid Action Models (PHAMs), a realistic causal model for predicting the behavior generated by modern percept-driven robot plans.
Beetz, M., Grosskreutz, H.
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

A Parametric Hierarchical Planner for Experimenting Abstraction Techniques [PDF]

, 2003
This paper presents a parametric system, devised and implemented to perform hierarchical planning by delegating the actual search to an external planner (the "parameter") at any level of abstraction, including the ground one.
ARMANO, GIULIANO, CHERCHI G, VARGIU, ELOISA   +2 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Necessity of the inclusion of borders in value of cultivation and use trials in upland rice

Revista Agrogeoambiental, 2019
Experimental accuracy in crop research is directly affected by the size of plots. For this reason, researchers use empirical knowledge to determine plot size. There are also other important aspects for determining ideal plot size. These include the type
Marcelo Eduardo Forni de Mattos, Flávia Barbosa Silva Botelho, Gabriel Mendes Vilella, Douglas Goulart Castro, Bruno Manoel Rezende Melo, Tácio Peres da Silva   +5 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source