Results 141 to 150 of about 9,415,293 (298)

Experimental testing of fracture fixation plates: A review. [PDF]

Proc Inst Mech Eng H, 2022
Zhang S, Patel D, Brady M, Gambill S, Theivendran K, Deshmukh S, Swadener J, Junaid S, Leslie LJ.   +8 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Experimental testing of a prototype cantilevered liquid-nitrogen-cooled silicon mirror. [PDF]

J Synchrotron Radiat, 2023
Cutler G, Cocco D, Bentley B, Cervantes M, Chavez P, Chrzan J, DiMaggio S, Hussey R, Ilmberger J, Lindsay J, Lizotte E, McCombs K, Morton S, Paulovits G, Pearson K, Redding C, Smith N, Tokunaga K, Zehm D, DiMasi E, Padmore H.   +20 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Study on the construction of a model for particle size distribution of coal fines in the full wellbore of coalbed methane wells

Scientific Reports
During the drainage process of coalbed methane wells in the Panhe Block of the Qinshui Basin, severe coal fines production restricts productivity release.
Peng Kong, Min Zhou, Daichen Yao, Zhili Fan, Zhou Zhang, Hao Hu, Wanying Yu, Xiaofei Zhang, Qiang Zou   +8 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Computational Analysis and Experimental Testing of the Molecular Mode of Action of Gatastatin and Its Derivatives. [PDF]

Cancers (Basel), 2023
Vottero P, Wang Q, Michalak M, Aminpour M, Tuszynski JA.   +4 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Randomized experimental testing of new survey approaches to improve abortion reporting in the United States. [PDF]

Perspect Sex Reprod Health, 2022
Lindberg LD, Maddow-Zimet I, Mueller J, VandeVusse A.   +3 more
europepmc   +1 more source