Results 161 to 170 of about 9,415,293 (298)

High strain rate tensile testing using microscopic high speed photography

open access: yes, 1998
A method is presented that combines advanced experimental and numerical techniques in the determination of constitutive parameters. The general principle is that a specimen, producing a non-homogeneous stress state, is deformed rapidly.
Melin, L.Gunnar,   +2 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Performance Testing of Experimental Dowel Bar Retrofit Designs Part 1 - Initial Testing

open access: yes, 2003
An area of concern common to portland cement concrete (PCC) pavements is load transfer across joints and cracks. The current design standard for load transfer in new jointed PCC pavements and the rehabilitation of old PCC pavement is to place steel dowel
Schultz, Arturo E.   +2 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Experimental Testing of the Affective Consequences of Nostalgia. [PDF]

open access: yesPsychol Russ
Tsigeman ES   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy