Results 251 to 260 of about 1,244,078 (315)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Acoustic Source Localisation of Crack Initiation During Laser-Based DED: Experimental Validation and Challenges. [PDF]

Materials (Basel)
Ansari MJ, Arcondoulis EJG, Roccisano A, Schulz C, Schläfer T, Hall C.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Integrative Analysis of Triphala's Therapeutic Mechanisms in Periodontitis: Network Pharmacology-guided Investigation with Experimental Validation in Cellular and Animal Models. [PDF]

Oral Health Prev Dent
Zhao Y, Li S, Kreher D, Haak R, Fichter A, Schmalz G.   +5 more
europepmc   +1 more source

Integrative Systems Biology and Experimental Validation Unveil GALNT14 as a Novel Diagnostic Biomarker and Therapeutic Target for Sepsis. [PDF]

Hum Mutat
Zhu X, Zhai Y, Yao J, Chen Y, Ge W.
europepmc   +1 more source

CAD-Based Analysis and Experimental Validation of Registration Errors in Imageless Total Knee Arthroplasty. [PDF]

J Clin Med
Sohail M, Khalid S, Elahi MU, Kim HS.
europepmc   +1 more source

Experimental validation of metaheuristic-optimized control for standalone DFIG dynamic performance enhancement. [PDF]

Sci Rep
Soued S, Boureguig K, Chabani MS, Himair Swhli KM.   +3 more
europepmc   +1 more source

Experimental Validation of an Immune Cell Infiltration Signature in Psoriasis: Translating Computational Modeling to In Vivo Efficacy. [PDF]

J Clin Lab Anal
Zheng T, Xu R, Zhang J, Wen X, Huang H, Tang H, Zhang Z, Zeng C.   +7 more
europepmc   +1 more source