Results 91 to 100 of about 286,000 (316)

Design and Experimental Verification of Urban Rail Transit Flexible Formation Train Reconnection Functionality

Chengshi guidao jiaotong yanjiu
Objective During off-peak hours, large train departure interval is adopted for off-peak urban rail transit passenger flow, however, it is commonly faced with issues of low seat occupancy rates and high energy consumption.
CAO Chengpeng, CAO Haifeng, FU Zhenliang, CAO Chunwei, HAO Mingyuan   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Control System Design and Experimental Verification of Capsubot

, 2008
This paper is concerned with the development of the Capsule Robot (Capsubot) which can move with no external parts. It is easy to be constructed in small scale and maybe can be used for medical uses such as the endoscope since the Capsubot moves ...
Kamamichi, Norihiro, Furuta, Katsuhisa, Lee, Namkon, 李洪谊   +3 more
core  

PHOTONICS TECHNOLOGY AS A WAY FOR UPGRADING KEY TECHNICAL FEATURES OF RADIO-SIGNAL DELAY DEVICES

Российский технологический журнал, 2017
Based on the previous results for our investigations of various retarding materials for super-wide bandwidth long-term delay lines and shortcomings of the available fiberoptic delay links based on binary delay chain where semiconductor optical switches ...
T. N. Bakhvalova, M. E. Belkin, I. V. Gladyshev, S. A. Kudzh, A. S. Sigov   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Numerical Simulation of Heavy and Light Pollutants Motion as a Tool of Experimental Data Verification

, 2011
Computational Fluid Dynamics (CFD) codes including software ANSYS Fluent represent worldwide accomplished group of tools for fluid mechanics phenomena numerical simulations.
Tomas Hejzlar, Dalibor Micek, Ondrej Zavila, Lenka Herecova   +3 more
core   +1 more source

Integrated Network Pharmacology Analysis and Experimental Validation to Elucidate the Mechanism of Acteoside in Treating Diabetic Kidney Disease

Drug Design, Development and Therapy
Shu Jiao Zhang,1,2,* Yi Fei Zhang,1,2,* Xue Hui Bai,1,2 Meng Qi Zhou,1,2 Ze Yu Zhang,1,2 Shuai Xing Zhang,1,2 Zi Jing Cao,1,2 Lin Wang,1,2 Shao Wei Ding,1,2 Hui Juan Zheng,1,2 Yu Ning Liu,1– 3 Guo Yong Yu,1 Wei Jing Liu1– 3 1Dongzhimen Hospital ...
Zhang SJ, Zhang YF, Bai XH, Zhou MQ, Zhang ZY, Zhang SX, Cao ZJ, Wang L, Ding SW, Zheng HJ, Liu YN, Yu GY, Liu WJ   +12 more
doaj  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Approximation Based Safety and Stability Verification of Hybrid Systems

, 2011
"With the advent of computers to control various physical processes, there has emerged a new class of systems which contain tight interactions between the ""discrete"" digital world and the ""continuous"" physical world. These systems which exhibit mixed
Prabhakar, Pavithra
core