Results 111 to 120 of about 1,035,590 (321)

A functional approach to integrating database and expert systems [PDF]

, 1988
Tore Risch, René Reboh, Peter E. Hart, Richard O. Duda   +3 more
openalex   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Expert-Agnostic Learning to Defer [PDF]

arXiv
Learning to Defer (L2D) learns autonomous systems to independently manage straightforward cases, while deferring uncertain cases to human experts. Recent advancements in this field have introduced features enabling flexibility to unseen experts at test-time, but we find these approaches have significant limitations.
arxiv  

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

Optimal Expert Selection for Distributed Mixture-of-Experts at the Wireless Edge [PDF]

arXiv
The emergence of distributed Mixture-of-Experts (DMoE) systems, which deploy expert models at edge nodes, offers a pathway to achieving connected intelligence in sixth-generation (6G) mobile networks and edge artificial intelligence (AI). However, current DMoE systems lack an effective expert selection algorithm to address the simultaneous task-expert ...
arxiv  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Pharmacokinetics and expert systems as aids for risk assessment in reproductive toxicology. [PDF]

, 1987
Donald R. Mattison, Frederick R. Jelovsek   +1 more
openalex   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Improving Energy Efficiency in Manufacturing: A Novel Expert System Shell [PDF]

arXiv
Expert systems are effective tools for automatically identifying energy efficiency potentials in manufacturing, thereby contributing significantly to global climate targets. These systems analyze energy data, pinpoint inefficiencies, and recommend optimizations to reduce energy consumption.
arxiv  

Generic expert system shell for diagnostic reasoning [PDF]

, 1988
Wei-Han Chu
openalex   +1 more source